Hit Profiling / Lead Optimization Assays
Finalize hits and characterize compounds with ADME and toxicity assays. Compounds must have suitable pharmacokinetics to proceed with in vivo models and clinical trials. Profiling or characterization assay readouts can range from detailed microscopy analyses, changes in electrochemical gradients across membranes, functional assays with flow cytometry or LC/MS, to determine how differences at the atomic level can affect kinetics of each compound.
The life sciences companies of Danaher offer the following analytical and data management solutions to help with your screening:
- Molecular Devices ImageXPress HT.ai High Content Imaging System
- Molecular Devices FLIPR Penta High Throughput Cellular Screening System
- Beckman Coulter Life Sciences Vi-CELL BLU Cell Viability Analyzer
- Beckman Coulter Life Sciences CytoFLEX Flow Cytometer
- Molecular Devices SpectraMax iD5 Plate Reader
- Leica Microsystems Stellaris Confocal Microscope
- IDBS Polar Biopharma Lifecycle Management software
- SCIEX Echo MS System
- SCIEX ZenoTOF 7600 System
- Genedata Biopharma Platform software
Hit Profiling / Lead Optimization Assays Products
STELLARIS Confocal Microscope Platform
Next generation STELLARIS is a confocal microscope platform designed around your research needs. STELLARIS confocal microscopes can be combined with all Leica modalities, including FLIM, STED, MP, DLS, and CRS. The next generation STELLARIS confocal platform is your fast track to rewarding research. Power. Potential. Productivity.
View ProductsSpectraMax® i3x Multi-Mode Microplate Reader
Western blot, imaging, and injectors on one configurable microplate reader.
View ProductsImageXpress® HCS.ai High-Content Screening System
The ImageXpress HCS.ai High-Content Screening System captures your imagination with high-quality imaging and analysis, enabling you to acquire the crystal-clear images and robust data you need with ease.
View ProductsFLIPR® Penta High-Throughput Cellular Screening System
High-throughput kinetic screening for toxicology and lead compound identification
View ProductsVi-CELL BLU Cell Viability Analyzer
Fully automated trypan blue dye exclusion method High throughput 24 position carousel Supports 96 well plate Faster analysis time compared to Vi-CELL XR Single sign-on with Active Directory Facilitates 21 CFR Part 11
View ProductsZenoTOF 7600 System for Mass Spectrometry
A high-resolution mass spectrometry solution that combines powerful MS/MS sensitivity, fragmentation technology and a step-change in data independent acquisition.
View ProductsCytoFLEX Flow Cytometer
No. of Lasers : 1-3 Laser Configuration: VBR (25) Colors/Parameters (Detection Channels): Up to 13 Small Particle Detection: With violet laser enabled Automation-Ready?: Yes Plate Loader: Yes Extended Use Fluidics: Yes
View ProductsGenedata Biopharma Platform: Biopharma Automation & AI
Genedata transforms biopharma R&D through automation, advanced analytics, and AI. As the first biologics-native technology company, we lead digitalization and enable data-driven decision-making for biopharma organizations worldwide. The Genedata Biopharma Platform combines a unified data model with workflow automation and embedded AI to accelerate and optimize end-to-end discovery and development of biologics and other modalities.
View ProductsIDBS Polar
An enterprise lab informatics software platform with ELN, LES and LIMS capabilities designed to power scientific innovation.
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