Extraction Kits - Nucleic Acid
With our nucleic acid extraction kits, you can achieve reliable results, ensuring consistent yield, quality and integrity even for your most challenging samples.
Our genomic DNA (gDNA) purification kits ensure efficient recovery of high-quality DNA from diverse samples, offering consistent performance across different throughput levels. And our total RNA isolation kits prioritize optimal RNA integrity with the highest quality and yield. You can rely on these kits for robust foundations in molecular biology and genetic research, ensuring reproducibility and high-quality nucleic acid extractions.
Our DNA extraction kits stand out with proven capabilities, unmatched flexibility and scalability to overcome routine challenges associated with diverse organisms and a variety of sample types. These kits utilize our SPRI paramagnetic bead-based systems, designed with DNA quality, integrity, and yield as the most important kit specifications.
Our SPRI-based chemistry allows for precise plasmid purification and high-throughput gDNA extraction from various sample types. We have validated DNA extraction data from mammalian blood and tissues, eukaryotic and prokaryotic cells, and formalin-fixed paraffin-embedded tissue.
Shifting focus to RNA extraction, a critical process susceptible to degradation, our kits safeguard against degradation risks. Using a gentle binding process with SPRI paramagnetic beads, they preserve optimal RNA integrity and yield. These kits efficiently isolate high-quality total RNA from various samples, including blood preserved in PAXgene tubes, saliva and Swab Transport Media.
For viral RNA extraction, our RNAdvance Viral kit provides a versatile solution, streamlining the process and eliminating the need for filtration or centrifugation. Even challenging FFPE samples can be efficiently processed for RNA extraction using our SPRI-based chemistry.
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Features
Extraction Kits - Essential features
- Manual or automated, the nucleic acid isolation kits offer flexibility in processing various sample types and quantities, accommodating different laboratory workflows for nucleic acid extraction.
- Specifically designed for infectious disease and pathogen research, the viral RNA extraction kit generates high-integrity viral RNA with a demonstrated Limit of Detection (LoD) at 1 copy/μL for sensitive PCR-based applications.
- The kits isolate nucleic acids with high integrity, ideal for Next-Generation Sequencing (NGS) and various PCR-based applications.
- Leveraging fragment analysis, FormaPure XL RNA kits showcase the extraction of RNA with optimal integrity, even from tissue blocks that are decades old.
- The DNA extraction and purification kits designed for FFPE samples consistently yield genomic DNA (gDNA) isolates of superior purity and quality, demonstrated by their effective performance with 7 x 10 μM curls.
- In high-throughput settings, these nucleic acid extraction kits facilitate plasmid purification in a 96-well format, streamlining sample processing to enhance laboratory productivity.
Applications
Applications of Extraction Kits
- DNA and RNA extraction kits are essential in molecular biology research for applications such as gene expression analysis, PCR amplification, and Next-Generation Sequencing (NGS). These kits enable scientists to obtain high-quality genetic material for a variety of downstream experiments, contributing to advancements in understanding cellular processes and functions.
- DNA extraction kits are widely employed in forensic science for the isolation of DNA from crime scene samples, including blood, hair, or saliva. RNA extraction may also be applicable in certain forensic investigations. These kits assist forensic analysts in obtaining genetic profiles for identification purposes, aiding law enforcement agencies in solving crimes and establishing links between individuals and biological evidence.
- Extraction kits play a pivotal role in the production of monoclonal antibodies (mAbs). These kits are essential for isolating high-quality RNA from cells involved in the production of mAbs, ensuring the preservation of genetic materials and maintaining optimal RNA integrity.
- Extraction kits find extensive applications in cell line development, a critical aspect of biopharmaceutical research and production. These kits are designed to efficiently extract and purify genomic DNA from various cell types involved in cell line development.
Are the RNA extraction kits compatible with automation systems?
Yes, the kits offer automation-friendly features, making the RNA extraction process compatible with automated systems, streamlining workflows and increasing efficiency in the laboratory.
Can your kits handle a wide range of tissues, including decade-old tissue blocks?
Yes, our FormaPure XL Total RNA kits, backed by fragment analysis, demonstrate the isolation of RNA and DNA with the best possible integrity, even from decade-old tissue blocks.
Do the mRNA extraction kits support Next-Generation Sequencing (NGS)?
Absolutely. Our mRNA extraction kits, built on SPRI paramagnetic bead-based technology, ensure a reliable and efficient process for isolating RNA suitable for NGS and various PCR-based applications.
Can the extraction kits handle challenging sample types like formalin-fixed paraffin-embedded (FFPE) tissues?
Yes, SPRI paramagnetic bead-based chemistry allows efficient RNA and DNA extraction even from the most challenging FFPE tissue samples, eliminating the associated hazards of organic solvents.
What sets our total RNA extraction kits apart from others?
Our kits are meticulously designed to ensure optimal RNA integrity, prioritizing genetic material preservation, leading to consistent delivery of pure nucleic acids with the highest quality and yield.
Are the viral RNA extraction kits suitable for high-throughput applications?
Yes, our viral RNA extraction kit RNAdvance Viral is ideal for high-throughput applications, providing a versatile solution tailored for diverse input sample types and collection devices.
How do the reagent kits address the vulnerability of RNA to degradation?
The reagent kits facilitate a gentle binding process to SPRI paramagnetic beads, ensuring optimum RNA integrity during extraction, safeguarding against degradation-related pitfalls and ensuring reliable results.
Are the extraction kits suitable for extracting RNA from samples preserved in PAXgene and other RNA-preservation tubes?
Yes. The extraction kits efficiently isolate high-quality total RNA from blood samples preserved in PAXgene and other RNA-preservation tubes, ensuring a robust foundation for downstream applications.