Why It Matters

Translating Human-Relevant Models to Clinical Success​

Human-relevant models and spatial profiling are transforming drug discovery by providing more predictive, human-like data compared to traditional animal models and 2D cultures. Human-relevant models, such as organoids and 3D cell cultures, better mimic human biology, improving disease modeling, drug screening and precision medicine.

Spatial profiling further enhances these insights by mapping cellular interactions and biomarker distribution, aiding in personalized treatments for cancer, neurodegenerative diseases and autoimmune disorders. These technologies reduce reliance on animal testing, aligning with regulatory shifts and improving early toxicity assessments. By bridging the gap between preclinical research and clinical trials, human-relevant models and spatial profiling accelerate drug development, ensuring safer, more effective treatments reach patients faster.

The Life Sciences companies of Danaher provide integrated solutions for human-relevant models and spatial profiling, addressing the need for more predictive models in drug discovery. With advanced imaging, automation and AI-driven analysis, we enhance data accuracy, optimize drug response insights and drive the next generation of precision medicine.

Danaher Corporation

Danaher Corporation

Automation & Standardization

Automation and standardization enhance drug discovery by improving reproducibility, efficiency and reliability in human-relevant models like organoids and 3D cultures.​

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We see a way to boost in-house organoid production by 25 times compared to culturing cells by hand.

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Danaher Corporation

Expertise

We specialize in cultivating and analyzing microphysiological systems, like organoids, to enhance research integrity and accuracy for better decision-making.

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We see a way to reduce time to assay from 17 days to just 2 days with experiment-ready human-relevant models.

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Danaher Corporation

Mechanisms to Report on Drug Response

Understanding drug response is crucial to all drug discovery and development programs, as miscalculations can lead to failed clinical trials and patient harm.

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We see a way to train users 50% faster to image organoids and 3D cultures.

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Danaher Corporation

Decision Making with Real-Time Data

Quick access to insights demands tools for real-time analysis, data consolidation, reduced analysis time and faster insights delivery.​

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We see a way to increase assay sensitivity by 50% using AI-based phenotypic classification.

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