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STELLARIS Confocal Microscope Platform

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Next generation STELLARIS is a confocal microscope platform designed around your research needs.

STELLARIS confocal microscopes can be combined with all Leica modalities, including FLIM, STED, MP, DLS, and CRS. The next generation STELLARIS confocal platform is your fast track to rewarding research. Power. Potential. Productivity.

Next Generation STELLARIS Confocal Microscope

Next Generation STELLARIS Confocal Microscope

Next Generation STELLARIS Confocal Platform STELLARIS is a true confocal point scanning system, including a White Light Laser as excitation light source, an Acousto Optical Beam Splitter (AOBS) and a highly sensitive, prism-based spectral detection design with computer controlled adjustable bandwidth for all fluorescence channels. The extended detection range up to 850 nm plus the excitation range in the visible from 440 nm up to 790 nm (different models available on request) allow the application and separation of an extended range of spectrally overlapping fluorophores. Including TauSense, a set of tools based on fluorescence lifetime information, it provides an additional contrast, improved image quality and separation of spectrally overlapping fluorophores. LIGHTNING allows for optimal extraction of image details and maximum resolution, thus expanding the imaging portfolio both in the classical range and beyond the diffraction limit.

STELLARIS Personal Confocal Microscope

STELLARIS Personal Confocal Microscope

STELLARIS Personal Confocal Microscope Freedom to Image. Power to Discover. Take control of your imaging - on your budget and on your schedule. Unlock the power of high-quality imaging without high costs or steep learning curves. STELLARIS is a true confocal point scanning system with AI Denoise, Spectral Detection, Photon Counting Detectors, and Confocal Super Resolution! You can also increase productivity by integrating additional modalities — such as Autonomous Microscopy, API, SmartCORR, Digital Light Sheet, and more - into the STELLARIS platform. Leica Microsystems is proud to support your research with a fully equipped confocal microscope with 2 Power HyD S detectors and 1 Power HyD N detector, 3 VIS Laser Lines, 405 nm Laser, Motorized X-Y Stage, and Confocal LIGHTNING Super Resolution package. You can also upgrade with additional detectors (up to five in total) or add lasers and other options based on your current or future needs. Request a Quote Today! Built In Intelligence That Works for You: STELLARIS now introduces built in intelligence to enable smarter, sharper, and more efficient confocal imaging performance. Smart AI Denoise: On the fly, AI based denoising improves spatial and temporal signal and contrast during acquisition. Smarter Photon Detection Efficiency: The latest addition to the Power HyD detector family, Power HyD N, supports demanding multiplexed experiments under physiological conditions by enabling fast, high sensitivity detection in the far red and NIR range while minimizing dark noise. SmartCORR: Achieve sharper imaging in thick or dense samples with intelligent, adaptive correction of refractive index mismatches. Smart Microscopy: Combine intelligent detection, customized workflow implementation, and optimized data acquisition to reduce user dependency and improve reproducibility.

SpectraPlex for Spatial Biology

SpectraPlex for Spatial Biology

Save up to 80% of your precious sample and preparation time

SpectraPlex is a 3D high-multiplex imaging solution for the STELLARIS confocal platform, including a White Light Laser as excitation light source. It enables access to 3D high-multiplex spatial information across scales in one go (one round of labeling and imaging), with subcellular detail, and far beyond conventional multicolor imaging.

SpectraPlex enables the design of high-multiplex experiments in advance. explore and optimize panel options with the integrated Virtual Fridge and Design Panel functionalities. It generates automatically acquisition settings with minimal user interaction, offering intelligent guidance for experimental controls while keeping flexibility for the advanced user.

The Potential to discover more

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STELLARIS unique TauSense technology allows you to extract an extra layer of information from every sample and increase the scientific impact of your research. TauSense is comprised of application-oriented imaging tools based on fluorescence lifetime that you can use to explore the function of molecules within the cellular context.

  • TauContrast provides immediate access to functional information, such as metabolic status, pH, and ion concentration.
  • TauGating improves the quality of your images by removing unwanted fluorescence contributions.
  • TauSeparation helps you expand the combination of fluorescent signals in your experiment beyond the spectral options.
  • TauInteraction provides straightforward detection and quantification of molecular interactions (e.g. protein-protein interaction).

The Productivity to do more

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Streamlined setup and acquisition: ImageCompass, the STELLARIS smart user interface, provides users with an easy and intuitive way to set up even the most complex experiments with just a few clicks.

  • Simply fast: Superb image quality in real time and at full speed with the LIGHTNING super-resolution, Dynamic Signal Enhancement (DSE) powered by Aivia.
  • Intuitive User Interface: ImageCompass guides you from the experiment setup through acquisition.
  • Optimize your experiment: Tools such as LAS X Navigator are seamlessly integrated for straightforward imaging.

Access data that matter

Get high-quality results faster with Autonomous Microscopy powered by Aivia.

  • The AI-based rare event detection workflow for life science on STELLARIS autonomously detects up to 90 % of rare events in biological samples.
  • Radically shorten the data acquisition time by up to 70 %, as objects of interest are exclusively identified and recorded. Record only what you need to, saving valuable space on your hard drive.
  • Spend less time at the microscope: The autonomous rare event detection workflow requires only a fraction of the time you would usually need.
  • Conduct experiments that were previously not possible due to time constraints and complexity with Autonomous Microscopy powered by Aivia.

STELLARIS with WLL

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STELLARIS the only confocal system with an integrated WLL, combined with our proprietary Acousto-Optical Beam Splitter (AOBS) and the Power HyD detector family. Together with the unique TauSense technology, STELLARIS sets a new standard for the quality of images and quantity of information generated.

STELLARIS with White Light Laser can be combined with FAst Lifetime CONtrast (FALCON), STED, Deep In Vivo Explorer (DIVE), Digital Light Sheet (DLS), Cryo and CARS. STELLARIS maximizes the potential of these modalities and give you the power and potential to set new standards for research.

STELLARIS

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STELLARIS offers Spectral Detection, Photon Counting Detectors, and Confocal Super Resolution.

Multi-channel confocal imaging is easily attainable thanks to the smart user interface, ImageCompass, which guides you intuitively through your experiment set up and acquisition.

The POWER to see more

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The Power HyD detector family provides higher photon detection efficiency (PDE)* extremely low dark noise, and sensitive spectral detection from 410 to 850 nm.

  • Enhanced image quality: STELLARIS provides an ideal combination of brightness, resolution and contrast.
  • Complete spectral freedom: Our next-generation White Light Lasers allow you to simultaneously use up to 8 single excitation lines from across the spectrum. Image more fluorophore combinations than with any other confocal platform and use more labels in parallel, expanding your options into the NIR range.
  • Gentle Live Cell Imaging: Preserve your sample’s integrity and image for longer periods of time through efficient signal acquisition at the lowest required levels of illumination

*2x higher Photon Detection Efficiency (PDE) compared to conventional multi-alkali Photomultiplier Tubes (PMT) and 3x higher in the extended red range.

Next generation STELLARIS. Your fast track to rewarding research.

Potential to discover more

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TauSense gives instant access to lifetime-based information, delivering additional insights to your experiments.

Productivity to do more

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The ImageCompass user interface enables you to acquire images with just a few clicks, even when doing complex experiments.

Power to see more

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The synergy between the Power HyD detector family, optimized scan optics, and White Light Laser (WLL) empowers you to obtain more accurate and reliable data to test your hypothesis with precision.

STELLARIS STED Stimulated Emission Depletion Microscope
Instruments

STELLARIS STED Stimulated Emission Depletion Microscope

Discover the STELLARIS STED Microscopes, combining confocal brilliance with advanced STED technology for unparalleled 2D and 3D nanoscale imaging.

STELLARIS DLS Digital Light Sheet Microscope
Instruments

STELLARIS DLS Digital Light Sheet Microscope

STELLARIS DLS enables confocal and light sheet microscopy on one system with fast imaging, reduced phototoxicity, and sample flexibility for live studies.

SpectraPlex for STELLARIS 3D High-Multiplex Solution for Spatial Discoveries
Instruments

SpectraPlex for STELLARIS 3D High-Multiplex Solution for Spatial Discoveries

Streamline panel creation, automate acquisition, and get reliable spatial biology data with advanced unmixing algorithms. Request a quote today.

STELLARIS DIVE Multiphoton Microscope
Instruments

STELLARIS DIVE Multiphoton Microscope

Stellaris 8 Dive multiphoton microscope offers flexible multicolor imaging (1 mm depth), a confocal software interface, and superb navigation. Request a quote!

STELLARIS CRS Coherent Raman Scattering Microscope
Instruments

STELLARIS CRS Coherent Raman Scattering Microscope

Explore the STELLARIS 8 CRS Microscope for high-speed, high-resolution, label-free chemical imaging and detailed 3D insights with multimodal capabilities.

STELLARIS Cryo Confocal Microscope
Instruments

STELLARIS Cryo Confocal Microscope

STELLARIS 5 Cryo Confocal Light Microscopes for cryo-electron tomography workflow with 3D-targeted structures. Boost your productivity. Request a quote!

Viventis Deep Dual View Light Sheet Microscope
Instruments

Viventis Deep Dual View Light Sheet Microscope

The Viventis deep dual view light sheet microscope delivers high-resolution 3D imaging of live and cleared samples with adaptable optics and dual-view detection.

Mica Microhub
Instruments

Mica Microhub

Explore the Mica microscope with 85% fewer steps to the first image & 33% less time to start. Access confocal imaging to simplify workflows & efficient results.

STELLARIS FALCON FLIM Microscope
Instruments

STELLARIS FALCON FLIM Microscope

STELLARIS 8 falcon is a fully integrated fluorescence lifetime imaging system that supports Förster resonance energy transfer. All-in-one multimodal imaging.