Pool Screening Solutions for Cell Line Development
Screening selected pools of cells producing mAbs with required attributes includes cell culture maintenance, imaging and cellular analysis. Cell culture maintenance can be automated on a Beckman Coulter Life Sciences Biomek i-Series Automated Workstation while antibody titer is quickly assessed with the Beckman Coulter Life Sciences ValitaTiter IgG quantitation assay and Molecular Devices SpectraMax plate reader. Pool screening and monoclonality assurance can be automated within a Molecular Devices ClonePix 2 Mammalian Colony Picker and automated imaging can be performed on the Molecular Devices ImageXpress Pico.
Genedata Bioprocess increases the efficiency of the end-to-end cell line development workflow, encompassing plate management, pool and cell line tracking, data aggregation from instruments, selection decision-making, cell bank inventory and cell line history reporting. It facilitates workflow automation, barcoding, and high-throughput processes, capturing all data in a structured format to create a robust data foundation for predictive modeling and AI/ML.