Gene Modification and Analysis in Gene Therapy Workflows
The delivery of guide RNA (gRNA) and CRISPR-associated (Cas) nucleases varies depending on the target cell type and gene editing strategy. Automate your chemical transfection workflow and ensure consistency with a Beckman Coulter Life Sciences Biomek i-Series Integrated Workstation.
Post-modification, assess cell count and viability to confirm successful delivery and minimize cytotoxic effects using the Beckman Coulter Life Sciences Vi-CELL BLU Cell Viability Analyzer. Downstream phenotypic analyses, such as mitotic analyses and fluorescent imaging, can be performed on a Leica Microsystems STELLARIS Confocal Microscope Platform or automated on a Leica Microsystems Mica Microhub. Automatically capture and analyze gene editing outcomes, including imaging and other fluorescent assays, using the Genedata Biopharma Platform. With the software, register every component of a CRISPR-mediated gene therapy, including Cas and sgRNA-encoding plasmids, delivery systems (e.g., LNPs, viral vectors) and purified final products.
Collect and track experiment and instrument data with the IDBS Polar Biopharma Lifecycle Management software.
Gene Modification and Analysis Products
Mica Microhub
The world’s first Microhub. More than a highly automated microscope, Mica unites widefield and confocal imaging in a sample protecting, incubating environment. With the simple push of a button, you have everything you need - all in one place - to supercharge fluorescence imaging workflows and get meaningful scientific results faster.
View ProductsSTELLARIS Confocal Microscope Platform
Next generation STELLARIS is a confocal microscope platform designed around your research needs. STELLARIS confocal microscopes can be combined with all Leica modalities, including FLIM, STED, MP, DLS, and CRS. The next generation STELLARIS confocal platform is your fast track to rewarding research. Power. Potential. Productivity.
View ProductsVi-CELL BLU Cell Viability Analyzer
Fully automated trypan blue dye exclusion method High throughput 24 position carousel Supports 96 well plate Faster analysis time compared to Vi-CELL XR Single sign-on with Active Directory Facilitates 21 CFR Part 11
View ProductsBiomek i5 Automated Workstation Liquid Handler
<p>Optimize dependability and walk-away time. The Biomek i5 is a recent addition to our liquid handling portfolio, representing the best of what has made Biomek an industry-leading brand - combined with enhancements suggested by customers around the globe.</p> <ul> <li>Ideal for medium- to high-throughput workflows</li> <li>25 deck positions</li> <li>0.5 µL-1,000 µL (Multichannel) or 0.5 µL-5,000 µL (Span-8) pipetting volume ranges</li> <li>Single Multichannel head (96/384) or Span-8 pipetting with gripper</li> </ul>
View ProductsAvanti® JXN-26 Series
Enhance your workflow with the Avanti JXN-26 high-speed Centrifuge System 6.0 L Max Capacity 26,000 RPM 81,770 x g
View ProductsBiomek i7 Automated Workstation
The most powerful and comprehensive Biomek available. High-throughput 45 deck positions 0.5 - 5,000 µL pipetting volume range Single or dual heads
View ProductsIDBS Polar
An enterprise lab informatics software platform with ELN, LES and LIMS capabilities designed to power scientific innovation.
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