Assaying
Organoids facilitate many different assay types to be carried out. ATP assays, gene expression, protein translation, spatial analyses, metabolomics and toxicology studies are just a few possible analyses. Consider the following analytical instruments to help with your primary or secondary analyses.
- SCIEX ZenoTOF 7600 Mass Spectrometers provide high resolution MS/MS and deliver a high depth of coverage on masses present in organoid cultures. Analyze your MS data with Genedata’s Expressionist Software.
- Molecular Devices FLIPR Penta High Throughput Cellular Screening System will help automate toxicology, kinetic and functional screening assays. Screen and identify your lead compounds with ease using the Molecular Devices ScreenWorks Software.
- Spatial analysis of organoids has applications for gene expression, disease modeling and drug localization. Leica Microsystems’ Stellaris 5 & 8 DLS Confocal microscopes are tools to understand how architecture influences outcomes. Coupled with the LAS X Microscope Software, Stellaris will help you digitally reconstruct your organoid in three dimensions.
- Cell surface protein expression can be analyzed with a Beckman Coulter Life Sciences CytoFLEX Flow Cytometer and Cytobank analysis software.