Select Starting Material
Employing organoids for disease modeling and drug discovery starts with the selection of the proper cell type(s). Pluripotent stem cells, established cell lines, primary cells or tissue samples are just a few possible starting cell types. For disease modeling, genetic modification (e.g., CRISPR) of stem cells or confirmation of primary samples should be conducted prior to organoid development. If using organoids for drug screening, it is important to incorporate a control population. Our 3D Ready™ Organoids are a convenient, easy-to-use solution for researchers who want to use organoid models for their own research but are held back by the high barriers to entry. Other important considerations include selection of media, reagents and consumables.