Mass Spectrometers Instruments
We offer comprehensive, integrated liquid chromatography-mass spectrometry solutions designed to provide answers to your questions. These meticulously tested and seamlessly coordinated mass spectrometry workflows offer a complete solution, catering to novice and experienced users across diverse market applications, allowing you to select the workflows that best suit your laboratory needs. The groundbreaking integration of acoustic droplet ejection (ADE) and the open port interface (OPI), coupled with the quantitative capabilities of the mass spectrometer, results in an ultra-high sample throughput system that combines speed, scalability, and unwavering data quality. Our cutting-edge software excels in identifying both small molecule metabolites and investigating large molecule catabolites. Its advanced processing logic, tailored for peptides, proteins, and antibody drug conjugates (ADCs), facilitates rapid and confident catabolite identification and provides insight into the metabolism of even the most intricate large molecules. High-throughput MetID and soft spot analysis can be conducted through information-dependent acquisition (IDA) workflows for swift and efficient identification and analysis of metabolites in both small and large molecules.
Echo® MS+ Systems
Streamline and simplify your workflows, delivering more and faster with software engineered for all your SCIEX mass spectrometry systems. SCIEX OS software revolutionizes mass spectrometry research, providing unparalleled efficiency, depth, and new potential to your analytical workflows.
Our accurate QTOF mass spectrometers portfolio is designed to meet a diverse range of analytical needs, offering exceptional speed, robustness, mass resolution, and mass accuracy for both complex research projects and high-throughput testing applications. Whether you require comprehensive coverage for in-depth analysis or a simplified system for efficient testing, our accurate quadrupole technology offers industry-leading acquisition speeds and innovative acquisition workflows like SWATH acquisition, ensuring your laboratory is prepared for upcoming challenging projects, while unique source designs and efficient data file structures reduce downtime and optimize data management for increased productivity.
ZenoTOF 7600 System for Mass Spectrometry
Experience accurate mass spectrometry with our sensitive ion trap solutions, offering full-scan MS, exceptional QTRAP resolution, and an extensive mass range. Harness the potential of advanced features like precursor ion scanning, true triple quadrupole precursor ion analysis, and neutral loss scanning for precise and comprehensive detection, ensuring your analytical needs are met with unparalleled precision and flexibility. Uniquely, we offer additional MS scans for identifying, characterizing, and quantifying samples, opening up new possibilities. Whether for high-throughput analyses or in-depth investigations of analytes, the next-generation technology empowers you to achieve both quantification and discovery without compromising sensitivity. Our diverse range of QTRAP systems caters to your specific laboratory needs and budget, providing the tools to tackle complex workflows with ease. With this LC-MS/MS system, you can effortlessly meet regulatory and analytical requirements for detecting trace-level compounds while maintaining the highest sensitivity.
Triple Quad™ 5500+ System - QTRAP® Ready
QTRAP® 6500+ System
QTRAP® 4500 System
SCIEX Triple Quadrupole LC-MS/MS systems stand at the forefront of analytical technology by delivering precise quantitation and robustness for answering important quantitative questions. With the patented Turbo V ion source and various scan types like multiple reaction monitoring (MRM), precursor, neutral loss and enhanced product ion scans, scientists are empowered to develop powerful methods for complex matrices with outstanding levels of selectivity and sensitivity.
Triple Quad™ 6500+ System
Triple Quad™ 5500+ System - QTRAP® Ready
Triple Quad™ 4500 LC-MS/MS System
Triple Quad™ 3500 LC-MS/MS System
Overview of Mass Spectrometers Instruments
Whether you’re analyzing small or large molecules or biologics, our range of triple quadrupole and high-resolution LC-MS mass spectrometers are designed to deliver precise results and dependability you can count on to drive real impact from your scientific research.
Our cutting-edge, accurate mass QTOF systems come in convenient benchtop configurations and are suited for everything from routine, to high-throughput, and high-resolutions workflows ideal for complex quantitative and qualitative assays.
The QTRAP and triple quadrupole systems provide the highest levels of MS/MS sensitivity and selectivity. Designed for challenging assays requiring utmost sensitivity and precision, they also boast robustness you can rely on day after day.
Product Highlights/Key Features of our Mass Spectrometers
SCIEX mass spectrometers are designed to help you break new ground by pushing the limits of speed and sensitivity in quantitative and qualitative analyses.
- Our Triple Quadrupole and QTRAP linear ion trap mass spectrometers are long known for their quantitative merit. They are capable of handling a wide range of compounds, from low to high mass ions, and excel in both positive and negative polarities. QTRAP functionality helps deal with selectivity issues, and offers simultaneous confirmation or identification without sacrificing data quality.
- Our high resolution, accurate mass quadrupole time-of-flight (QTOF) systems offer comprehensive compound coverage and workflow flexibility with wide intra-scan linear dynamic range and a variety of scan functions. These compact, benchtop instruments allow you to dig deeper into your samples with ultra-fast acquisition rates and give unbiased, complete MS/MS information with SWATH acquisition.
- Acoustic ejection mass spectrometry redefines the future of high-throughput analyses with contactless sampling of up to 1 sample per second. The Echo® MS+ system delivers high-quality data, analytical flexibility, and high sample throughput so you can make informed decisions, today.
- Tunable electron activated dissociated (EAD) fragmentation technology is available on the ZenoTOF 7600 and provides several unique benefits. Characterization of key structural attributes of large molecules, fragment post-translationally modified peptides while retaining critical MS/MS information, as well as elucidation of positional isomers on both small molecules and lipids are just a few of the capabilities.
- Exclusive to SCIEX, QTRAP technology is built into every Triple Quad, ready to be upgraded and future-proof laboratories. Functionality like enhanced product ion scans enable improved confidence, while MRM3 workflows push quantitation levels through matrix interreferences.
- icIEF-UV/MS technology accelerates biotherapeutic development by directly coupling icIEF-UV (imaged capillary isoelectric focusing with UV detection) charge variant analysis with high-resolution mass spectrometry detection for intact proteins.
- The integration of capillary electrophoresis (CE) with electrospray ionization (ESI) into a single dynamic process within the same device delivers high-efficiency electrophoretic and hydrodynamic separation at ultra-low flow rates to enhance sensitivity and quantitation while reducing ion suppression bias.
- Quality ion sources deliver more ions to the mass analyzer, increasing coverage over a wide analyte range. While the Turbo V ion source is renowned for its reliability and efficiency, the technology continues to evolve with flexible options to cover a broader range of applications and flow rates, quickly.
- Delivering maximal information in minimal time, with little fear of missing an analyte, our DIA (data independent acquisition) techniques have evolved since they were first commercialized in 2012. Offering high specificity, reproducibility, and precision, gain comprehensive MS/MS coverage at new depths of detection.
Applications of Mass Spectrometry Systems
Whether you are identifying antibody drug conjugates to treat cancer cells, monitoring lifesaving immunosuppressant drug doses, or analyzing components to combat contaminant adulteration, SCIEX LCMS products help make possible what was once impossible. Key application areas include:
- Life science research: From biomarker discovery to translational research and beyond, life science research laboratories use SCIEX LCMS tools to uncover crucial biological insights with unparalleled precision and efficiency.
- Pharma and biopharma research: SCIEX LCMS tools offer analytical strategies for addressing the complexities of developing modern therapeutics, from discovery to delivery are necessary for pharmaceutical and biopharmaceutical research laboratories.
- Clinical research and diagnostics: These laboratories are engaged in multiple workflows from discovering and validating new biomarkers to executing end-to-end validated workflows for high throughput testing in the clinic.
- Forensic testing: Forensic testing labs depend on the accurate quantitation of low levels of drugs and metabolites in complex biological samples with high precision and accuracy, as well as the detection of previously undetectable potent novel psychoactive substances.
- Food and beverage testing: Staying compliant and up to date with today’s food safety standards is necessary for these labs. Detecting and identifying targeted and non-targeted analysis at or below maximum residue limits with high-quality data is imperative.
- Environmental testing: Environmental labs rely on LCMS to help them respond quickly and meet new and changing regulations with confident results for the screening, identification, and quantitation of low-level chemical contaminants.
ZenoTOF 8600 system for Mass Spectrometry
Triple Quad™ 4500 LC-MS/MS System
QTRAP® 6500+ System
Triple Quad™ 6500+ System
Triple Quad™ 3500 LC-MS/MS System
QTRAP® 4500 System
Intabio ZT System
SCIEX 7500+ system
ZenoTOF 7600 System for Mass Spectrometry
Triple Quad™ 5500+ System - QTRAP® Ready
Echo® MS+ Systems
X500R QTOF System
X500B QTOF System
FAQs
Mass spectrometry is a powerful, precise, and sensitive analytical technique that is used to identify and quantify known and unknown molecules in a wide variety of samples types and sample complexity, as well as elucidate structural and chemical properties of molecules of interest. These molecules can be present in solid, liquid, or gas samples.
Mass spectrometers are the sorting, detecting, and counting component of the analytical technique referred to as mass spectrometry. They are exceedingly sensitive and specific and, together with a sample delivery system, have the capability of answering many kinds of quantitative and qualitative questions about samples.
They work by measuring the mass-to-charge (m/z) ratio of one or more molecules, called ions, present in a sample. Samples are typically introduced via a liquid chromatography system (LC) and are ionized in the ion source. From here, they are moved through the mass spectrometer via electric and magnetic fields to the detection element where they are measured and recorded.
Many types of gas chromatography (GC), LC, and MS systems exist today enabling an ever-increasing number of applications in science and technology. The needs of users vary, as do the chemical form and amount of sample available for analysis, thus vendors have developed a wide variety of designs. Fundamentally, however, there are a several major components:
- Ionization source: This element is responsible for creating the ionization of samples and produces a beam of charged particles (either negative or positively charged).
- Mass Analyzer: Once ionized, the ions are separated according to their mass-to-charge (m/z) ratio by the mass analyzer.
- Detector: The separated and sorted ions are then measured and sent to a data system for analysis. The m/z ratios are stored along with the relative abundance. A mass spectrum is plotted against their intensities where each peak in a mass spectrum represents a unique m/z in the sample, and the height of each peak connotes its abundance.
Our mass spectrometers are designed to help you break new ground by pushing the limits of speed and sensitivity in quantitative and qualitative analyses. They deliver the speed and performance that ensures the results are the best the can be.
Yes, our mass spectrometers are designed to adapt to changing research needs, as the company emphasizes continuous innovation in efficiency, automation, usability, and optimized workflows.
SCIEX mass spectrometry solutions are ideal for a wide variety of laboratories and industries, from routine and standard studies to advanced and complex analyses. LCMS systems are an essential tool for the analysis of a range of samples, offering insights into the concentration, structure, isotopic distribution, and biological properties of molecules in the given sample. SCIEX LCMS systems have been innovated to be versatile, enabling high sensitivity quantitation and qualitative workflows without compromising on speed, accuracy, reliability or robustness. SCIEX offers a broad portfolio of LCMS solutions to meet customer’s specific laboratory requirements and budgets.
Cutting-edge mass spectrometers need cutting-edge software tools to help get the most out of our high-performance LCMS systems. The SCIEX suite of software includes workflow and application modules to supplement instrument control software. Workflow modules combine high-performance and simplicity with add-ons for optimized quantitative and qualitative workflows, whereas application modules translate that data into conclusive results fast.
All mass spectrometers require some expertise in analytical chemistry, mass spectrometry principles and instrument-specific knowledge. SCIEX offers diverse and flexible learning options for expert-led training, both virtually and in-person. With courses and training available for instrument operation, troubleshooting and maintenance, software, method development and validation, as well as application and workflows, SCIEX is prepared to prepare you, effectively.