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Intabio ZT System - Rapid Charge Variant Analysis in Minutes

The process of identifying individual charge variant components and interpreting their structural differences conventionally takes weeks and requires the use of multiple instruments, with multiple manual steps.

With the Intabio ZT system - separation, quantitation and identification of individual charge variants can be achieved in minutes on a single platform

Danaher Corporation

Innovating to Solve Your Cell Line Development Pain Point

Danaher Corporation

Cut out risk, cut out information gaps. Get the required information to make confident decisions, fast.

Product quality characterization with rapid multi-attribute monitoring of intact biotherapeutics and identification of charge variants throughout the drug development pipeline.

Leverage key analytical functions with microfluidic chip-based technology

Accelerate candidate selection by achieving separation, quantitation, and direct identification of biopharmaceutical charge variants and their proteoforms with icIEF-UV/MS via the integrated Intabio ZT system.

  • Separation of charge variants with capillary isoelectric focusing (iCIEF)
  • Quantitation with real-time UV detection
  • Electrospray ionization for further mass spectomeyrt identification

Danaher Corporation

Let Biologics Explorer software do the heavy lifting

Maintain data continuity with a single workflow producing one, accessible dataset, where UV peaks correlate with MS peaks. Let Biologics Explorer software built by Genedata do the heavy lifting with pre-built workflows for charge variant analysis.