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ZenoTOF 8600 system for Mass Spectrometry

ZenoTOF 8600 system for Mass Spectrometry

Extraordinary discoveries demand extraordinary proof. The ZenoTOF 8600 system delivers new levels of sensitivity, combined with the versatility of EAD and Zeno-trap enabled workflows.

An accurate mass platform evolved from SCIEX leadership in fast, sensitive, and resilient quantitation

Welcome to the forefront of scientific innovation. In the quest to make groundbreaking biological discoveries, the quality of data and the technology used are paramount.

The SCIEX ZenoTOF 8600 system combines proven technology from our most sensitive triple quad with our most versatile Zeno trap-enabled QTOF, delivering 10x better sensitivity than the current SCIEX accurate mass system across many new and established accurate mass approaches.

This translates not only into lower limits of quantitation, but also into newly enabled approaches for making biologically relevant discoveries supported by high-quality data.

Extraordinary performance in both core and transformative workflows

The ZenoTOF 8600 system represents a leap forward in mass spectrometry, offering noteworthy sensitivity and precision. Performance improvements in MS1 and MS2 enhance data quality across a wide range of workflows.

10x sensitivity*

With 10x greater sensitivity in MS1 and MS2 and the integration of SCIEX triple quad technology, this system enables precise identification and fast, sensitive quantitation of low-abundance biomolecules across targeted, DIA, and DDA methods.

* Compared to the ZenoTOF 7600+ system

Discover more with comprehensive data analysis

ZT Scan DIA 2.0 delivers high-speed, broad molecule support with enhanced Q1 window selectivity for improved quantitative accuracy and identification.

Deliver on important timelines

Performance-driven speed enhancements maximize throughput and enable faster acquisition of high-quality EAD spectra.

Transforming data into actionable insights

SCIEX OS 4.0 software streamlines workflows with features for method development, real-time QC, and data acquisition.

Features

Attaching biological relevance to discoveries in your research demands the highest possible data quality and the ability to harness new technology in unprecedented ways.

Ionization source

The OptiFlow Pro ion source incorporates the reliability and efficiency of the Turbo V ion source while enabling fast switching across flow rates.

Scan speeds of up to 858 Hz

When using ZT Scan DIA 2.0, the system can operate at MS/MS scan rates of up to 858 Hz.

Mass Guard technology with optical detector

The combination of Mass Guard technology and a new optical detection system allows operation at higher ion currents while protecting the instrument from contamination.

ZT Scan 2.0 DIA for all molecule types

Flexible mass range and compound parameters extend functionality across diverse workflows with minimal optimization.

High-energy EAD

Acquire higher-quality EAD spectra faster across molecule types, extending electron-based fragmentation into negative ionization with up to 50 eV.

ZenoTOF versatility

The Zeno trap enables enhanced sensitivity by accumulating ions prior to rapid TOF pulsing.

Integrated innovation

SCIEX OS 4.0 enables performance tracking, system health monitoring, and automated tuning.

More energy efficient

The ZenoTOF 8600 system uses dry roughing pumps, reducing electricity consumption by up to 24% compared to oil-sealed pumps.