Our multi-mode microplate readers are equipped to perform both top and bottom readings. These readers are also upgradeable to improve performance and streamline laboratory workflow. Some models of these plate readers also permit the incorporation of additional assay technologies like imaging, AlphaScreen, or Western blot detection. Opting for a unified unit that integrates various microplate technologies and detection modes can be particularly advantageous when space in the lab is limited. Our SoftMax® Pro Software, an industry leader for microplate reader control and data analysis, includes the latest version, SoftMax® Pro 7.3 GxP Software, which ensures comprehensive FDA 21 CFR Part 11 compliance through secure features and streamlined workflows, safeguarding data integrity. Our seamlessly integrated on-board injectors, equipped with high-performance SmartInject® Technology and overflow protection, allow you to expand your laboratory's potential by incorporating flash applications such as dual luciferase and ATP assays, enhancing reagent mixing and preventing spillage-related damage.
FEATURES
Essential features of our Multi-detection Plate Readers
- Crafted for enduring reliability, our versatile multi-mode microplate readers for every lab ensure sustained performance over the years. Adhering to industry norms, it's essential to periodically validate and document instrument performance to meet regulatory standards, including assessing monochromator or filter-based wavelength emission, precision, and stability and evaluating optical system steadiness through tests for low and high signal spikes and drift.
- Our multi-user microplate readers stand out for their unparalleled quality. Whether you're conducting high-throughput experiments, intricate cell-based assays, or intricate imaging studies, these readers consistently provide accurate quantification and data, ensuring the quality of your results.
- Engineered for lasting performance, our multi-mode microplate readers are built to withstand the demands of diverse experiments. Their robust construction and broad dynamic range make them a dependable tool for achieving consistent and meaningful results throughout extensive research projects.
APPLICATIONS
Applications of Multi-mode Microplate Readers in life science research
- Among our plate readers, the SpectraMax Mini ELISA plate reader offers a space-efficient design and three detection modes, which is particularly valuable for the efficient detection of target antigens within samples, streamlining the often time-consuming and labor-intensive ELISA assay development procedure, where the antibody binds to wells present in both 96- and 384-well microplates.
- Our readers are utilized in conducting pDNA template testing in mRNA characterization. These readers enable comprehensive analysis by accommodating various modes of detection, allowing researchers to assess the quality and characteristics of pDNA templates used in mRNA studies efficiently and accurately.
- Multi-mode microplate readers are pivotal for streamlining various stages of monoclonal antibody development, including antibody screening, cell culture maintenance, antibody titer assessment, pool screening, monoclonality assurance, and automated imaging.
- A multimode microplate reader is essential in cell line development for assessing cell viability and proliferation through absorbance, fluorescence, and luminescence assays.
- In oligonucleotide characterization, our reader is employed to verify the progress of synthesis reactions and determine reaction yields and efficiency by measuring absorbance, ensuring accurate synthesis of RNA oligonucleotides.
- Microplate readers also play a pivotal role in research and drug discovery, bioassay screening, quality control, nucleic acid and protein quantitation and analysis, microbiology and contaminant monitoring, and manufacturing within different settings.
FAQs
What are the different types of multi-mode readers available?
- FlexStation 3 Multi-Mode Microplate Reader:
This microplate reader integrates precise optics, fluidic transfer, and assay flexibility into one cohesive unit and accommodates 6–384 well plates.
- SpectraMax iD3 Multi-Mode Microplate Reader:
Featuring a large touchscreen and NFC functionality, this offers ease of use and accommodates 6–384 well plates for absorbance, fluorescence and luminescence detection.
- SpectraMax i3x Multi-Mode Microplate Reader:
Elevating its adaptability, this reader provides unlimited user upgradeable application modules, encompassing areas like western blot, imaging, and injectors, and can fit 6–1536 well plates.
- SpectraMax Paradigm Multi-Mode Microplate Reader:
Geared for increased throughput and efficiency, this instrument offers excellent performance and configurable options. It can accommodate 6–1536 well plates.
- SpectraMax M Series Multi-Mode Microplate Readers:
With triple-mode cuvette ports, validation tools, and compliance software, these configurable readers can fit 6–384 well plates.
- SpectraMax iD5 Multi-Mode Microplate Reader:
Featuring a large touchscreen and NFC functionality, this multi-user microplate reader can fit 6–384 well plates and measures 5 modes of detectionSpectraMax Mini Multi-Mode.
- Microplate Reader:
Positioned as an affordable option, this reader is accompanied by robust data analysis software and can fit 6–384 well plates.
How do absorbance, luminescence, and fluorescence detection work in our microplate readers?
Absorbance detection in microplate readers involves passing light of a specific wavelength through a sample. The sample absorbs a portion of this light, and the detector on the other side of the microplate well measures how much light was absorbed.
In microplate readers with fluorescence intensity (FI) detection, a light source excites a fluorescent molecule (fluorophore) at a specific wavelength. This excitation prompts the fluorophore to emit light at a higher wavelength, which is then detected by a photomultiplier tube.
Luminescence detection doesn't require a light source for excitation. Instead, it detects the light emitted by a sample during a 'flash' or 'glow' reaction. Flash luminescence is intense but short-lived, while glow luminescence is more stable but less intense and can last minutes or hours.
What to consider when choosing a multi-mode microplate reader?
When selecting a multi-mode microplate reader, consider factors such as the required detection modes (absorbance, fluorescence, luminescence), assay flexibility, throughput capacity, application compatibility, and data analysis capabilities to ensure it meets your specific research or experimental needs.
What are the advantages of our microplate readers?
Our multiple dedicated instruments under the category of microplate readers offer several advantages, including versatile detection modes (absorbance, fluorescence, luminescence), application-specific modules, user-friendly interfaces, high-throughput capabilities, advanced data analysis software, and compatibility with various plate types, enabling precise and efficient analysis for diverse research and experimental needs.