Primary Screening Assays
Iterate on screening hits discovered previously using more complex assays; for example, by performing dose response assays or by measuring gene expression. Primary screening will depend on aims and types of molecules being screened. Readouts can range from fluorescence analyses with a plate reader or cellular imaging to LC/MS traces to determine mass modifications.
Danaher’s operating companies offer the following analytical and data management solutions to help with your screening:
- Molecular Devices ImageXPress HT.ai High Content Imaging System
- Molecular Devices FLIPR Penta High Throughput Cellular Screening System
- Beckman Coulter Life Sciences Vi-CELL BLU Cell Viability Analyzer
- Beckman Coulter Life Sciences CytoFLEX Flow Cytometer
- Molecular Devices SpectraMax iD5 Plate Reader
- Leica Microsystems Stellaris Confocal Microscope
- IDBS Polar Biopharma Lifecycle Management software
- SCIEX Echo MS System
- SCIEX ZenoTOF 7600
- Genedata Screener software