Viventis Deep Dual View Light Sheet Microscope

Explore life in depth 

(Increased spatio-temporal resolution with dual Illumination and dual detection for single and multi-position experiments.) 

The Viventis Deep microscope helps you to expand the spatio-temporal understanding of your sample to its full depth, thanks to increased spatio-temporal resolution.

Achieve detailed volumetric imaging for a complete view of the sample with a patented combination of

• Dual illumination
• Dual view detection
• Multi-position
• Open top sample holder

You can even image large light scattering samples over time with outstanding quality for meaningful downstream analysis, while minimizing light dose and maintaining sample accessibility.

Explore life events with long-term imaging 

(Intestinal organoids label with FUCCI reporter to follow cell cycle dynamics. Courtesy of Franziska Moos. Liberali lab. FMI Basel (Switzerland).)

In a variety of model systems, including intestine, liver and human colon cancer organoids and zebrafish embryos, the gentle light sheet technology of the Viventis Deep microscope provides high image quality while preserving sample viability.

In addition, the advanced incubation solution and easy media exchange even during a running experiment preserves physiological conditions. Easily handle even more complex experimental conditions. To study responses and to ensure specific results, you can add drugs and use an optional photomanipulation arm during a running time-lapse.

Explore live and cleared samples flexibly

(Left: 40-h time-lapse of a human brain organoid. Courtesy of Akank¬sha Jain, Treutlein Lab ETH-DBSSE Basel, CH. Right: Z-stack image of a cleared 60-day-old human brain organoid. Courtesy of Professor Barbara Treutlein, ETH, D-BSSE Basel, Switzerland.)

The combination of live and fixed or cleared imaging experiments supports capturing both dynamic information and molecular context. Viventis Deep enables imaging of live and cleared samples in a single system by exchanging the detection optics.

The cleared-sample module accommodates diverse clearing media and refractive indices and supports samples from hundreds of micrometers up to 9x6x6 mm. Tiling, stitching, and computational clearing enhance workflows for imaging large, cleared samples, and help maintain crisp image quality throughout.