Mica Microhub
This changes everything.
More than a highly automated microscope, Mica unites widefield and confocal imaging in a sample protecting, incubating environment. With the simple push of a button, you have everything you need - all in one place - to supercharge fluorescence imaging workflows and get meaningful scientific results faster.
Now you can focus on your science, not figuring out your microscope.
- Access for all
Mica provides a clear sample overview and allows to easily change observation conditions with just a few clicks
- No constraints
4x more data with 100% correlation. Select the right modality in real time. Achieve physiological-like conditions thoughout your experiments
- Radically simplified workflows
Intelligent automation and AI-supported analysis enables greater efficiency and a faster track to publication
Mica Widefield Live Cell Microhub Automated Microscope
Simplify advanced live cell and fluorescence imaging. Get reliable, expert level microscopy results faster with extensive intelligent automation, AI-supported analysis, and an interface designed for ease of use. Perform long-term live cell experiments up to 4x faster than traditional widefield systems, capturing events that may previously have been missed. Easily get quality images as Mica automatically corrects the focus during experiments. Minimise phototoxicity and maintain optimal cell health with full environmental control. Ideal for long-term live-cell studies at near physiological conditions. MICA BENEFITS: ACCESS FOR ALL: Mica requires minimal technical input and gives consistent results every time, so all lab members can leverage microscopy to make more discoveries. NO CONSTRAINTS: Get true simultaneous capture of up to four labels without spatiotemporal mismatch – at near-physiological conditions for live cells, or with fixed samples. RADICALLY SIMPLIFIED WORKFLOWS: Intelligent automation and AI-supported analysis of diverse samples, such as tissues on slides or well plates, enable greater efficiency and a faster track to publication.
Mica WideFocal Live Cell Microhub Automated Microscope
Combine widefield and confocal imaging in an incubating environment and simplify advanced live cell and fluorescence imaging. Extensive intelligent automation, AI-supported analysis, and an easy-to-use interface help you achieve expert microscopy results without all the training. Perform long-term live cell experiments up to 4x faster than traditional widefield systems, capturing events that may previously have been missed. Easily get quality images as Mica automatically corrects the focus during experiments. Minimise phototoxicity and maintain optimal cell health with full environmental control. Ideal for long-term and dynamic live cell studies of organoids, spheroids, and 3D cultures. MICA BENEFITS: ACCESS FOR ALL: Mica requires minimal technical input and gives consistent results every time, so all lab members can leverage microscopy to make more discoveries. NO CONSTRAINTS: Visualize in widefield and switch effortlessly to confocal without ever moving your sample. Get true simultaneous capture of up to four labels without spatiotemporal mismatch – at near-physiological conditions for live cells, or with fixed samples. RADICALLY SIMPLIFIED WORKFLOWS: Intelligent automation and AI-supported analysis of diverse samples, such as tissues on slides or well plates, enable greater efficiency and a faster track to publication.
Mica 20x LWD Objective with Service Installation
20x long working distance objective for imaging on glass and plastic bottom carriers. To penetrate deeper into samples using everyday standard plastic-bottom multi well plates, this Long Working Distance (LWD) objective has been optimized for use with Mica. · No need to sacrifice image quality · No need for costly glass-bottom alternatives · Avoid the frustration of switching carriers and re-optimizing your sample preparation protocols Why is long working distance important? · Focus deeper, capturing clearer images even with thicker or non-adherent samples such as organoids, spheroids and zebrafish larvae · Get increased compatibility with high-skirt well plates · Improve access to outer wells of multi well plates Please note: This objective requires service installation to ensure correct installation and calibration. A half-day service visit by our expert team is added to ensure optimal performance and system compatibility.
Mica Widefield Microhub Automated Microscope
Simplify advanced fluorescence imaging through extensive intelligent automation, AI‑supported analysis, and an easy-to-use interface. Now all lab members can get expert microscopy results, regardless of experience. Ideal for exploration and high-throughput fluorescence imaging of fixed samples. MICA BENEFITS: ACCESS FOR ALL: Mica requires minimal technical input and gives consistent results every time, so all lab members can leverage microscopy to make more discoveries. NO CONSTRAINTS: Get true simultaneous capture of up to four labels for fast acquisitions. RADICALLY SIMPLIFIED WORKFLOWS: Intelligent automation and AI-supported analysis of diverse samples, such as tissues on slides or well plates, enable greater efficiency and a faster track to publication.
Mica WideFocal Microhub Automated Microscope
Combine widefield and confocal imaging in an easy-to-use platform and simplify advanced fluorescence imaging. By streamlining workflows and reducing complexity through intelligent automation, AI-supported analysis, you can get expert microscopy results without all the training. Ideal for high-resolution imaging of thick or complex samples. MICA BENEFITS: ACCESS FOR ALL: Mica requires minimal technical input and gives consistent results every time, so all lab members can leverage microscopy to make more discoveries. NO CONSTRAINTS : Visualize in widefield and switch effortlessly to confocal without ever moving your sample. Get true simultaneous capture of up to four labels for fast acquisitions. RADICALLY SIMPLIFIED WORKFLOWS: Intelligent automation and AI-supported analysis of diverse samples, such as tissues on slides or well plates, enable greater efficiency and a faster track to publication.
Access for all
Everyone can now leverage microscopy to make more discoveries.
Mica provides a clear sample overview and allows you to easily change observation conditions with just a few clicks.
- 85% fewer steps to the first image
- 33% less time to the first image
- 50% of the training time
No constraints - 4x more data with 100% correlation
The Microhub enables you to simultaneously capture all four labels of different structures in a single acquisition for widefield or confocal, without ever moving your sample. This overcomes the spatiotemporal mismatch between labels of moving objects during sequential acquisition. All are powered by our patented FluoSync technology, a fast and gentle method for multicolor fluorescence imaging.
No constraints - Select the right modality in real time
Mica unifies transmitted and fluorescence light imaging modalities. You can select from multiple imaging modalities all within one Microhub, including widefield, confocal, THUNDER imaging, LIGHTNING, Z-stacks, time-lapse and more.
This enables you to
- generate fast overviews with widefield at low magnification
- gradually zoom in on the regions of interest
- switch to confocal when and where needed without ever moving the sample to a different system
3D Cell Culture, 7d spheroid formation of U343 cells. tfLC3 EGFP and mRFP + DAPI + WGA Alexa680. Objective: 20x NA 0.70 DRY
No constraints - Achieve physiological-like conditions thoughout your experiments
Live cell experiments require the cells to be in optimal shape. Typically, 2D and 3D cells in media require the temperature and the pH (via CO2) in the environment to be controlled. Stable nutrition and ion concentrations require the evaporation to be minimal. Some experiments even demand the O2 to be mimicked closer to physiological levels. Mica can provide the right conditions in the live cell configuration.
- Mica is an incubator: The entire encapsulated inner sample space can be climate controlled (temperature, CO2 and humidity regulation) and offers ideal conditions for short and long-term live cell observation.
- From dark to light: Mica also enables you to enjoy a brightly lit lab—freeing you from the constraints of sitting in a dark room for hours monitoring your experiment.
Formation of 3D spheroids from 1000 stably transfected MDCK MX1-GFP cells per well (left half) and 1000 U2OS cells per well (right half). Time-lapse acquisition over 60 hours, with 30-minute intervals. Green, GFP. Gray, integrated modulation contrast.
Radically simplified workflows
Intelligent automation and AI-supported analysis enable greater efficiency and a faster track to publication.
- Reduce over 60% of process steps through system intelligence
- Reduce time and effort from sample to insight by simplifying your entire workflow
- Enable 100% reproducibility and repeatability throughout your experiment
U2OS cells were labelled with SiR-Actin, TMRE (mitochondria activity), CellEvent™ (caspase activity), and DAPI (nuclei). 63x magnification, widefield mode.
The Microhub era is now!
Experience the future.
| Contrasting Method(s) | Brightfield, Fluorescence, Integrated Modulation Contrast |
| Long Working Distance | No |
| Microscopy Technique | Confocal Microscopy |
| Microscope Stage Type(s) | Motorized |
| Microscope Camera Option(s) | Integrated |
| Microscopy Software Available | 2D Anaylsis, 3D Acquisition (Z-Stacking), 3D Analysis, Deconvolution, Documentation, Live Cell Imaging, Multichannel Acquisition, Multiposition Acquisition, Super Resolution, Tile Stitching, Time Lapse Imaging |
| Has Eyepiece | No |
| Microscope Type(s) | Inverted Microscope, Inverted Microscope, Digital Microscope |
| Has Resonance Scanner | No |
| Microscope Laser Type | Fixed Wave Length |
| Microscope Environmental Control | Box |
| Microscope Group | Light Microscope |
| Application(s) | Cell Biology;Cancer Research;Live Cell Imaging;Organoids and 3D Cell Culture;Model Organisms in Research;Neuroscience |
STELLARIS Confocal Microscope Platform
STELLARIS delivers confocal imaging with TauSense WLL & AI-powered Aivia analysis for deeper insights in less time. Request a quote now.