Analytical Solutions l Multiple modalities. Simplified workflows.
Powering today’s pipelines. Ready for tomorrow’s therapies.
As modalities evolve, your analytical strategy must keep up. Our flexible, scalable solutions grow with your pipeline—from discovery to delivery.
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Why It Matters
Enabling Confident Decisions at Every Stage of the Therapeutic Lifecycle
From early-stage R&D and drug target validation to analytical method development and CMC scale-up, analytical laboratories are essential in ensuring the success and safety of therapeutics. These labs focus on key questions related to identity, purity, potency, stability and safety, to analyze product and critical quality attributes.
The Life Sciences companies of Danaher support these efforts with integrated solutions spanning LC-MS, capillary electrophoresis, chromatography, flow cytometry, imaging and digital data management. Our offerings enable scientists to access the appropriate tools for deriving insights from fully traceable and well-structured data.
As regulatory requirements tighten and pipeline diversity increases, the need for integrated, adaptable analytical workflows is more critical than ever. Our goal is to help labs speed up processes, reduce risks and uphold scientific rigor from development through scale-up.
Modalities
Cell Therapy
Regulatory requirements mandate that Cell Therapy developers document identity, purity, dose, safety and potency before clinical release. Explore solutions that verify your batch quality, consistency and readiness for release.
Gene Therapy
Comprehensive characterization data on off-target effects, enzyme activity, vector design and raw materials are crucial to guarantee safety and compliance. We offer solutions to verify that your gene therapies meet performance standards and regulatory guidelines.
mRNA
In vitro processes can face challenges with RNA length variation, stability, impurities and safety. Maintaining RNA integrity is crucial for stability and therapeutic effectiveness. Learn how we can support your RNA analytical characterization needs.
Antisense Oligonucleotide
Unlock the potential of antisense oligonucleotide therapies with seamless analytical consistency and top-tier reagent quality control. Keep your analytical lab at the forefront by ensuring scalable data collection and analysis for operational excellence.
Small Molecules
High-throughput screening of small molecule drug candidates demands robust and sensitive analysis to ensure optimal results. Our automated platforms and enterprise software efficiently streamline the entire process from hit selection to lead validation.
Monoclonal Antibodies
Multiple labs facilitate monoclonal antibody characterization, each with unique assay needs. We provide solutions at every stage, from sequence verification in genomics labs to testing product and critical quality attributes in analytical labs.
Enabling Faster, Data-Driven Drug Development
Analytical development demands a high level of adaptability, resourcefulness and access to the latest technologies to ensure precision, efficiency and scalability across various therapeutic programs. Method development also presents significant challenges, especially when designing, validating and optimizing methods for new modalities or regulatory standards.
The Life Sciences companies of Danaher can help you select the right analytical tools, along with automation, software analysis and data management solutions, to help ease these challenges. Our goal is to help you speed up the introduction of new treatments to the market. Ultimately, this enables you to focus on what matters most: delivering high-quality data and supporting the successful development of life-saving treatments.
Lack of scalable and reproducible workflows?
We see a way to screen 45 drug discovery candidates for quality assessment in 4 minutes.
SCIEX | High-Throughput Screening Echo® MS+ system with ZenoTOF 7600 system
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We see a way to accelerate ELISA processing speeds by 4x for complex biology applications
Molecular Devices | SpectraMax multi-mode readers
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We see a way to reduce experiment execution by 7000 hours.
IDBS | Polar
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Inefficient and fragmented characterization of complex modalities?
We see a way to accelerate chromatography data analysis workflows 8-16x
Genedata | Genedata Chromatics
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We see a way to generate aggregation data for 96 samples in as little as 15 minutes
Beckman Coulter Life Sciences | Valita Agg Pure Assay Kit
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We see a way to improve recovery and consistency of your biotherapeutic sample by greater than 80%, significantly accelerating the drug development process.
Phenomenex | Biozen LC columns
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Is poor data management leading to siloed systems, inconsistent results and limited insight across early-stage and preclinical studies?
We see a way to to drive efficiency by eliminating manual tasks, improving data integrity, and reducing reporting timelines by up to 80%
IDBS | Polar
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We see a way to design smarter clinical trials to improve the success rate by 20%
Genedata | Genedata Profiler
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We see a way to reduce time required for HT-MS data analysis by up to 80%
Genedata | Genedata Expressionist
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FAQs
What analytical methods are required for cell therapy product characterization?
Product characterization occurs throughout the development and manufacturing of cell therapies. Analytical methods are chosen based on the specific parameters or attributes to be tested. Some common analytical methods include:
- Flow cytometry is used to evaluate cell viability, identity, purity or potency. Beckman Coulter Life Sciences' flow cytometry systems streamline workflows to ensure accurate and consistent results.
- Gene expression analysis methods like NGS, PCR, qPCR and dPCR, assess plasmid integrity, vector copy number, gene expression levels and detect excipients or contaminants.
- Immunoassays are useful for analyzing secreted proteins and peptides to ensure safety. Abcam’s immunoassay kits ensure precision, reliability and efficiency for various research needs.
- Imaging techniques provide qualitative and quantitative data on identity, cytotoxicity, viability, protein expression and localization, as well as batch release testing. The Life Sciences companies of Danaher provide imaging technologies that range from automated digital microscopy to high-throughput confocal cell imaging system.