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improve the recovery and consistency of your biotherapeutic sample by more than 80%, significantly accelerating the drug development process.
Phenomenex | Biozen™ LC Columns
Reduce Non-specific Adsorption to Increase Chromatographic Efficiencies
Non-specific adsorption (NSA) complicates chromatographic analysis of biologics, causing long column passivation, high standard deviations and broad peaks.
Biozen™ LC Columns, featuring advanced bioinert technology, minimize NSA from metal interactions—reducing passivation time and enhancing reproducibility, sensitivity and data quality.
Modern LC Column Chemistries for Robust Biotherapeutic Characterization
Phenomenex delivers innovative chromatographic solutions for biopharmaceutical analysis, offering advanced columns and sample prep tools designed for robust large molecule characterization.
MS Friendly Oligo & mRNA Characterization via Size Exclusion Chromatography (SEC)
50mM Ammonium Acetate, pH 7 at 80°C (representative chromatograms)
Biozen™ Native RP for Antibody Drug Conjugate (ADC) Drug-Antibody Ratio Analysis by LC-UV-MS Analysis
Representative Chromatograms of ADC, Padcev®
Characterization of Digested sgRNA via LC-MS with Biozen™ Oligo C18
Sequence confirmation, impurity profiling, & PS diastereomers ID of 100nt sgRNA
Identification of Unique Adeno-Associated Virus (AAV) Serotypes via Retention Times (RT) with SEC
Representative chromatogram of AAV1 and tabulation of RT for other serotypes on Biozen™ dSEC-7
Resources
Phenomenex
A Suitable Size Exclusion Column for Efficient Adeno-Associated Virus Aggregate Analysis
Poster
Phenomenex
Size Exclusion Chromatographic (SEC) Method for Oligonucleotides Using Heated Columns
Poster
Phenomenex
sgRNA and Cas9 mRNA Characterization by Ion PairReversed Phase Liquid Chromatography Coupled to HRMS
Technical Article
Phenomenex
Utilizing Biozen™ Native RP-5 Column for Rapid RPLC-HRMS Separation and Identification of Native, Intact Antibody Drug Conjugate Species
Technical Article