Automation in Proteomics Sample Preparation
Proteomics analyses and cell-based assays are useful for understanding the complex interplay of protein–protein interactions and understanding protein structure and function within cells. Preparing samples for such assays can be daunting, especially for comparative proteomics, where researchers must manage a large number of samples or navigate diverse assay types. Ensuring accurate and reliable results across various experimental conditions and sample sizes calls for careful attention to eradicate inconsistencies and ensure quality proteomics data.
Automation can greatly improve precision in isolating and preparing individual cells for understanding cellular heterogeneity and diverse protein expression patterns. Manual proteomic sample preparation and handling of large sample sets can lead to variations in the sample preparation process and affect the reproducibility of assays. Incorporating automated workflow steps or processes can help to eliminate these inconsistencies. Streamlining and standardizing sample preparation protocols, integrating robust assay design and process monitoring solutions, can ensure reliable and high-quality proteomics data.
The Automation Advantage
Automated solutions, such as the Beckman Coulter Life Sciences Biomek i7 Workstation, can significantly enhance the efficiency and dependability of sample preparation. By aiding in sample preparation and generation of high-quality data, the Beckman Coulter Life Sciences Biomek i7 Workstationcan facilitate the precise quantification of peptides for mass spectrometry and support biomarker discovery.¹
Beckman Coulter Life Sciences Biomek i-Series instruments can also be integrated into flow cytometry workflows, extending the advantages of automation to the entire spectrum of cytometric sample preparation and processing. With the capability to consistently process hundreds of samples per day, these instruments provide the scalability needed for single-cell proteomics and the advancement of cutting-edge therapies.¹
Automate to Elevate
Proteomics sample preparation is as diverse as the methods used to analyze samples. Consistency and reproducibility are important when optimizing proteomic assays. Talk to an expert from the Life Sciences companies of Danaher Corporation to learn how to standardize assay preparation and reach your CQAs faster.