Proteins play a crucial role in nearly all cellular activities and interactions. Key categories of proteins used in research include cytokines, which trigger immune responses; growth factors to support cell culture in laboratories; and enzymes, which accelerate biochemical reactions. Our catalog features a wide range of native and recombinant proteins and peptides for your research needs.
Proteins and peptides are essential cellular components composed of amino acids, differing primarily in length and complexity. Peptides tend to be shorter and structurally simpler, while proteins can adopt various conformations that influence their multiple cellular functions. Since a protein’s structure determines its activity and can be modified, understanding its structure is key to uncovering its functional roles. Functional studies provide valuable insights into the diverse roles proteins play within the cell.
Accelerate your experimental design with our extensive selection of recombinant and native types of proteins complemented by our antibody offerings. Achieve high consistency and generate reproducible data with our wide range of proteins and peptides, including our premium bioactive proteins designed for optimal activity and stability. Keep your research moving forward with fusion-tagged proteins for target studies without the need for specific antibodies, verified blocking peptides for reagent specificity validation, and protein controls to strengthen the reliability of your results.
Selecting the right expression system is crucial when choosing a recombinant protein. We offer a diverse range of high-quality proteins produced in various expression systems, ensuring you find the best fit for your experimental needs. As a trusted supplier of proteins for a range of applications, we provide a comprehensive selection of bioactive research-grade proteins, delivering high-quality solutions for your research.
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Active Proteins
Biologically active proteins allow for the study of numerous experimental processes. Our active proteins provide versatility for a variety of research needs. They are critical tools for research applications such as cell culture, functional assays, and pre-clinical drug discovery. In high-sensitivity applications, their consistent performance ensures reproducibility. Our catalog includes premium-grade bioactive proteins that are engineered for exceptional purity, activity, and lot-to-lot consistency.
Native Proteins
Our catalog of native proteins, derived from over 10 species, including humans, mice, and rats, offers indispensable tools for cutting-edge research. These high-quality proteins are validated for applications such as functional studies, ELISA, western blot, and flow cytometry. They cater to diverse experimental needs by offering both biologically active and non-active variants, all free from tags or modifications.
Peptides
Peptides are versatile molecules integral to various research applications. Our catalog features a wide array of native, synthetic, and recombinant peptides derived from over 70 species. With offerings tailored to meet diverse research needs, our peptides are essential tools for advancing biochemical and biomedical studies. Their versatility makes them valuable in functional assays, structural biology, mass spectrometry, and beyond.
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Recombinant Proteins
Recombinant proteins are engineered variants of native proteins generated through recombinant DNA technology to enable large-scale production of a specific protein. Our recombinant proteins offer consistency with no batch-to-batch variability, ensuring reproducible results in every experiment. They provide a reliable and continuous supply, eliminating concerns about fluctuations in availability. We provide two types of recombinant proteins tailored to different research needs: Bioactive-grade proteins and premium-grade bioactive proteins. Our bioactive and premium bioactive proteins are designed to deliver exceptional performance in cell culture and functional studies.
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Tagged Proteins
Tagged proteins play a crucial role in making the purification process simpler and more efficient. Researchers can easily detect, quantify, purify, and study proteins, as well as explore their interactions and structures by attaching specific tags. Our catalog offers a wide selection of recombinant proteins, each with different tags. These tags make proteins easier to work with and improve their solubility, stability, and functionality.
Features
- Our recombinant proteins offer high purity, batch-to-batch consistency, and bioactivity.
- Our latest premium-grade proteins are produced in mammalian cell lines under animal-free conditions, ensuring ultra-low endotoxin levels (<5 EU/mg). Utilizing mammalian expression systems allows for proper protein folding and accurate post-translational modifications, optimizing bioactivity. These proteins closely mimic their native state, providing reliability and consistency for various applications.
- Developed by a team of expert protein scientists, each batch undergoes rigorous validation using cutting-edge technology to guarantee consistent quality in integrity, purity, concentration, mono-dispersity, and proper folding.
- Our native proteins retain their structure and modifications, ensuring optimal functionality and reliability for applications requiring biologically authentic protein characteristics.
Applications
- Functional assays: Our bioactive proteins can be used to study cellular responses, signaling pathways, and protein interactions, providing insights into biological processes and mechanisms.
- Control and validation: Our proteins and peptides serve as positive controls to validate antibody specificity and ensure accurate detection of target proteins in samples for numerous applications, including ELISA, western blotting, IHC, flow cytometry, and more.
- Protein-protein interaction studies: Proteins and peptides are utilized in assays such as pull-downs or co-immunoprecipitations to investigate interactions with other proteins, contributing to the understanding of complex cellular networks.
- Structural biology: Our high-purity proteins can aid in crystallization and structural analysis techniques like X-ray crystallography or cryo-electron microscopy, to determine protein structures.
- Mass spectrometry: Our proteins and peptides can serve as standards or references in mass spectrometry analyses to identify and quantify proteins in complex biological samples.
- Assay development: Our proteins and peptides are integral in developing and validating new assays for research purposes, including high-throughput screening and biomarker discovery.
- Cell culture: Our native growth factors and cytokines support the precise demands of cell culture. Our premium bioactive proteins can be used in functional assays to assess cellular responses.
What are peptides and proteins?
Peptides are short chains of amino acids, typically fewer than 50 residues in length, involved in processes like signaling and regulation. Proteins are longer and more complex, consisting of one or more polypeptide chains that perform a wide range of functions in the body, from catalyzing reactions to providing structural support and considerably more.
How are proteins utilized in drug discovery?
Proteins are used in drug discovery to identify potential drug targets, such as enzymes or receptors involved in disease processes. They are also employed in high-throughput screening to test the efficacy of compounds, helping to identify promising candidates for further development.
How are recombinant bioactive proteins produced?
Recombinant bioactive proteins are created by inserting recombinant DNA into an expression system, such as mammalian, bacterial, yeast, or insect cells, to produce large quantities of a specific protein. These proteins are designed to elicit a biological response and are produced with high purity and consistency for reliable research results.
What are some examples of proteins used in research?
A wide range of proteins is used in research, including Recombinant Human TNF alpha, Recombinant Human IL-1 beta, Recombinant Human IGF1, Recombinant Human beta Catenin protein (Tagged), Recombinant Human Osteopontin, Recombinant Human SIRP alpha Fc Chimera, and many more.