PA 800 Plus Pharmaceutical Analysis System
Flexible platform for multiple analytical assays with a temperature controlled capillary for the utmost data reproducibility and confidence.
Characterize therapeutic molecules with confidence on the PA 800 Plus system.
Perform consistent and compliant biotherapeutics characterization faster than ever
With the PA 800 Plus system, you can confidently safeguard the success of your biologics, run multiple characterizations from a single system that biopharma labs depend on, and produce qualitative and quantitative analyses with speed and confidence.
The PA 800 Plus system is a robust analytical, kit-based platform that can help you with:
-
Monoclonal antibody and next-generation protein applications
- Purity/Heterogeneity with gold standard CE-SDS in minutes
- Glycan analysis with award-winning Fast Glycan technology
- Charge heterogeneity with fast and simple CZE or with hi-res cIEF
-
Gene therapy and nucleic acid applications
- mRNA purity and integrity analysis
- Capsid protein purity
- AAV Empty vs. Full
- Plasmid and linear double-stranded DNA (dsDNA) analysis
- Small RNA or DNA analysis
-
Cell therapy
Key features
-
Multiple applications, one platform
Run multiple characterizations from a single system to improve your operational efficiency and effectiveness. -
Raw unmanipulated data
Have the confidence critical to both you and regulatory agencies for product submission and commercialization with raw, unmanipulated data. -
Reproducibility matters
Get repeatable results with exclusive recirculating liquid coolant to control separation temperature precisely. -
Portability matters
Easily transfer methods using robust, automated assays with proven portability ‐ ideal for global multi-user, multi-instrument.
Resources
All
Sorting
Newest
Resources
pdf
Upgrade Your SCIEX Capillary Electrophoresis Instruments Today
Announcement of Windows 10 compatibility upgrade for SCIEX Capillary Electrophoresis Instruments, highlighting benefits, features, and package options.
pdf
PA 800 Plus Start-Up Kit Flyer
Overview of start-up kits for the PA 800 Plus system by SCIEX, detailing included kits, consumables, and chemistries for instrument installation and operation.
pdf
ssDNA 100-R Kit Application Guide
qhis document provides instructions for sample preparation using the ssakA NMM-o hitK ft also provides instructions for data acquisition and data analysis using the PO haratqj poftwareK qhe ssakA N...
pdf
PA 800 Plus Pharmaceutical Analysis System SDS-MW Analysis Kit Application Guide
This document is provided to customers who have purchased SCIEX equipment to use in the operation of such SCIEX equipment. ... This document is copyright protected and any reproduction of this docu...
pdf
Size distribution analysis of residual host cell DNA fragments in lentivirus by CGE-LIF
The use of dsDNA 1000 kit and PA 800 plus to analyze DNA from host cell of AAV of gene therapy interest.
pdf
High-precision lentivirus titer determination and protein profiling
There are various challenges during lentivirus production including virus stability, toxicity of the virus to the host cell lines, and limited ability to properly characterize the active virus product. As a result, monitoring product quality is critical. Titer is one of the critical quality attributes (CQA) for lentivirus production from lab scale to GMP manufacturing. This technical note describes a method that offers a more accurate titer for lentivirus than ELISA and can also be utilized for profile-based purity assessment. This easy-to-use SDS-CGE method is aso amenable to automated analysis of the Lentiviral proteome with high resolution, excellent quantitation capability and great reproducibility. An easily applicable two step sample preparation and fluorescent labeling protocol is also described.