PA 800 Plus Pharmaceutical Analysis System
Capillary electrophoresis (CE) on the PA 800 Plus system enables ultra-high quality separation day in and day out for the development of proteins and next generation therapeutics.
Achieve a better understanding of protein purity, nucleic acid purity and integrity, protein charge heterogeneity, capsid protein purity, and glycan distribution. Overcome the challenges of an ever-changing pipeline with a single platform designed to minimize method development and maximize innovation.
Characterize therapeutic molecules with confidence on the PA 800 Plus system
Perform consistent and compliant biotherapeutics characterization faster than everWith the PA 800 Plus system, you can confidently safeguard the success of your biologics, run multiple characterizations from a single system that biopharma labs depend on, and produce qualitative and quantitative analyses with speed and confidence.
The PA 800 Plus system is a robust analytical, kit-based platform that can help you with:
Discover kit-based workflows that support core industry assays
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Monoclonal antibody and next-generation protein applications
- Purity/Heterogeneity with gold standard CE-SDS in minutes
- Glycan analysis with award-winning Fast Glycan technology
- Charge heterogeneity with fast and simple CZE or with hi-res cIEF
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Gene therapy and nucleic acid applications
- mRNA purity and integrity analysis
- Capsid protein purity
- AAV Empty vs. Full
- Plasmid and linear double-stranded DNA (dsDNA) analysis
- Small RNA or DNA analysis
Key features of PA800 Plus system
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Multiple applications, one platform
Run multiple characterizations from a single system to improve your operational efficiency and effectiveness. -
Raw unmanipulated data
Have the confidence critical to both you and regulatory agencies for product submission and commercialization with raw, unmanipulated data. -
Reproducibility matters
Get repeatable results with exclusive recirculating liquid coolant to control separation temperature precisely. -
Portability matters
Easily transfer methods using robust, automated assays with proven portability ‐ ideal for global multi-user, multi-instrument.
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Liquid temperature control
Even the slightest temperature variations can throw off your results. Exclusive recirculating liquid coolant enables the precise control of separation temperature in the capillary.
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Multiple injection modes
Ensure consistent, reproducible results with precise control. Get top-notch resolution with electrokinetic injection, tackle sample ionic strength with hydrodynamic injection, and master sensitivity with field-amplified sample stacking.
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Separation voltage
Strike the perfect balance between resolution and analysis time. Harness up to 30 kV separation voltage to tailor for your workflow and sample needs.
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Detection wavelength
Boost the signal-to-noise ratio for specific analytes and ensure spot-on, reliable results by adjusting a wide range of detection wavelengths.
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Capillary length
Switch up the size to boost separation.
Enhance selectivity for specific analytes and achieve superior resolution by adjusting the capillary length and choosing the right capillary coating.
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Detector type
Achieve high sensitivity or detect lower concentrations by switching between UV and LIF detectors based on your needs.
Benefits of PA 800 Plus Pharmaceutical Analysis System
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Flexibility
Gain valuable insights into quality attributes of biotherapeutics with kit-based assays and customizable features to address the evolving drug development pipeline.
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Quality
Achieve the resolution and reproducibility you need using industry and regulatory trusted technology, and meet data management needs with platform compatibility.
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Portability
Develop and lock down methods applicable to QC or regulated environments. Easily transfer methods between instruments or sites using robust kit-based workflows with proven portability.