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Optima™ AUC

  • Enables sample recovery
  • Avoids dilution effects
  • Analyzes samples in a matrix-free environment
  • Has minimal buffer constraints

Beckman Coulter introduced the first AUC sample characterization instrument to help the scientific community power new discoveries. That tradition continues into the 21st century with the new Optima™ AUC system.

This latest tool is the most robust technology for providing data used to determine protein molecular weight in basic protein research and quantification of aggregation levels for academic and biopharma research.

Features

Improved Data Quality

  • Higher radial resolution
  • Better signal to noise ratio than ProteomeLab
  • 11x more vertical pixels for interference optics
  • Enables precise analysis of complex systems at discrete wavelengths (up to 20) in minimal time

Analyzes a wide array of particles in native, matrix-free conditions, including:

  • Proteins
  • Nanoparticles
  • Peptides
  • Polymers
  • Micelles
  • Liposomes
  • Extracellular vesicles
  • Drug conjugates
  • Viral payload

Provides data which can answer more critical questions than any other comparable technique, including:

  • Shape
  • Mass
  • Diameter
  • Stoichiometry
  • Heterogeneity
  • Association
  • Aggregation
  • Purity
  • Formulation

Easier to Use

  • User-friendly touchscreen display indicates intuitive progression of experimental design.
  • Remote monitoring capabilities let you set up, monitor and extract data from virtually any location.
  • Compatibility with ProteomeLab XL cells and rotors
  • Toggle optics expedite workflow preparation
Resources
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pdf
Protein Purification Aggregation Solution
Protein aggregation is a biological phenomenon that occurs when destabilized proteins interact abnormally. Centrifugation is a useful tool for isolating and characterizing protein products.
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Assessing The Quality Of Adeno-Associated Virus Gene Therapy Vectors By Sedimentation Velocity Analysis - AUCINSIGHTS
Assessing the quality of adeno-associated virus gene therapy vectors by sedimentation velocity analysis ... INTRODUCTION ... Since the first gene therapy study in the late 1980s, there has been an ...
pdf
Analytical Ultracentrifugation Macromolecule Characterization In Solution
Brochure on Beckman's Optima AUC Centrifuge, focusing on academia applications.
pdf
A Guide To Winning A Shared Instrumentation Grant (SIG)
The Shared Instrumentation Grant (SIG) Program provides funds for purchasing shared-use instrumentation not typically supported by other funding programs sponsored by the National Institutes of Hea...
pdf
Multi-Wavelength Analytical Ultracentrifugation Of Human Serum Albumin Complexed With Porphyrin
Analytical Ultracentrifugation (AUC) is the method of choice to characterize colloidal systems under physiological solution conditions. ... Recently, a novel multi-wavelength (MWL) detector on Beck...
pdf
Comparing Data Quality & Optical Resolution Of The Next Generation Optima AUC To The Proven Proteomelab On A Model Protein System
Abstract ... AUC provides a matrix-free environment that allows the near-native state characterization of a wide range of molecules. ... Our recently launched Optima AUC is the only commercially av...