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AB139945

Anti-MYCT1 antibody

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(6 Publications)

Rabbit Polyclonal MYCT1 antibody. Suitable for WB and reacts with Rat, Human, Mouse samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Human MYCT1.

View Alternative Names

MTLC, MTMC1, MYCT1, Myc target protein 1, Myc target in myeloid cells protein 1

1 Images
Western blot - Anti-MYCT1 antibody (AB139945)
  • WB

Unknown

Western blot - Anti-MYCT1 antibody (AB139945)

Lane 1:

Western blot - Anti-MYCT1 antibody (ab139945) at 1 µg/mL

Lane 2:

Western blot - Anti-MYCT1 antibody (ab139945) at 2 µg/mL

All lanes:

Rat lung tissue lysate at 15 µg

Predicted band size: 27 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Rat, Mouse, Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human MYCT1. The exact immunogen used to generate this antibody is proprietary information.

Q8N699

Specificity

ab139945 will detect both isoforms of MYCT1

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Sample Prep & Detection Kits

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1-2 µg/mL", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
Affinity chromatography purified via peptide column.
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity).
See full target information MYCT1
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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

iScience 26:107609 PubMed37664593

2023

MYCT1 attenuates renal fibrosis and tubular injury in diabetic kidney disease.

Applications

Unspecified application

Species

Unspecified reactive species

Xin Li,Qiu-Ling Fan,Tian-Kui Ma,Cong Liu,Hang Shi,Yuan-Yuan Sun,Yue Wang,Dong-Xue Ding,Ao Tang,Yu Qin,Qi Yang,Hong Ding,Hang-Yu Li,Wei-Neng Fu

iScience 25:103955 PubMed35281731

2022

MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes.

Applications

Unspecified application

Species

Unspecified reactive species

Dong-Xue Ding,Yue Wang,Wei Yan,Wei-Neng Fu

Frontiers in oncology 10:564733 PubMed33680912

2021

MYCT1 Inhibits the Adhesion and Migration of Laryngeal Cancer Cells Potentially Through Repressing Collagen VI.

Applications

Unspecified application

Species

Unspecified reactive species

Peng-Peng Wang,Si-Yu Ding,Yuan-Yuan Sun,Yun-Hui Li,Wei-Neng Fu

PLoS genetics 16:e1009176 PubMed33137164

2020

Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors.

Applications

Unspecified application

Species

Unspecified reactive species

Emily M Schleicher,Ashna Dhoonmoon,Lindsey M Jackson,Kristen E Clements,Coryn L Stump,Claudia M Nicolae,George-Lucian Moldovan

Acta histochemica 122:151576 PubMed32778238

2020

miR-34a-5p suppresses the invasion and metastasis of liver cancer by targeting the transcription factor YY1 to mediate MYCT1 upregulation.

Applications

Unspecified application

Species

Unspecified reactive species

Xiao-Ping Xu,Xiang-Qun Peng,Xin-Min Yin,Yi Liu,Ze-Ya Shi

OncoTargets and therapy 11:1323-1331 PubMed29563811

2018

CREB promotes laryngeal cancer cell migration via MYCT1/NAT10 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Zhao-Xiong Zhang,Wan-Ni Zhang,Yuan-Yuan Sun,Yun-Hui Li,Zhen-Ming Xu,Wei-Neng Fu
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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