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Gemini™ pH Flexible LC

Gemini™ pH Flexible LC

Twin-NX technology HPLC columns. Extend your column lifetime

Gemini columns are rugged reversed phase HPLC and PREP LC columns that offer extended lifetime at pH 1-12 conditions and excellent stability for reproducible, high efficiency separations. The Gemini family contains a variety of useful akyl and phenyl phases bonded to fully porous organo-silica particles.

Gemini 5 µm C18 110 Å, LC Column 75 x 21.2 mm, AXIA Packed, Ea

Gemini 5 µm C18 110 Å, LC Column 75 x 21.2 mm, AXIA Packed, Ea

Gemini 10 µm C8(3) 100 Å, LC Column 100 x 30 mm, AXIA Packed, Ea

Gemini 10 µm C8(3) 100 Å, LC Column 100 x 30 mm, AXIA Packed, Ea

Gemini 5 µm NX-C18 110 Å, LC Column 250 x 50 mm, AXIA Packed, Ea

Gemini 5 µm NX-C18 110 Å, LC Column 250 x 50 mm, AXIA Packed, Ea

Gemini 5 µm C6-Phenyl 110 Å, LC Column 250 x 50 mm, AXIA Packed, Ea

Gemini 5 µm C6-Phenyl 110 Å, LC Column 250 x 50 mm, AXIA Packed, Ea

Gemini 10 µm C8(3) 100 Å, LC Column 250 x 30 mm, AXIA Packed, Ea

Gemini 10 µm C8(3) 100 Å, LC Column 250 x 30 mm, AXIA Packed, Ea

Gemini 10 µm C8(3) 100 Å, LC Column 250 x 21.2 mm, AXIA Packed, Ea

Gemini 10 µm C8(3) 100 Å, LC Column 250 x 21.2 mm, AXIA Packed, Ea

Gemini 10 µm C8(3) 100 Å, LC Column 100 x 50 mm

Gemini 10 µm C8(3) 100 Å, LC Column 100 x 50 mm

Gemini 10 µm C8(3) 100 Å, LC Column 250 x 50 mm, AXIA Packed, Ea

Gemini 10 µm C8(3) 100 Å, LC Column 250 x 50 mm, AXIA Packed, Ea

Gemini 10 µm NX-C18 110 Å, LC Column 100 x 4.6 mm, Ea

Gemini 10 µm NX-C18 110 Å, LC Column 100 x 4.6 mm, Ea

Gemini 3 µm C18 110 Å, LC Column 100 x 3.0 mm, Shipped in Formic Acid, EA

Gemini 3 µm C18 110 Å, LC Column 100 x 3.0 mm, Shipped in Formic Acid, EA

Twin-NX technology HPLC columns. Extend your column lifetime

Gemini columns are rugged reversed phase HPLC and PREP LC columns that offer extended lifetime at pH 1-12 conditions and excellent stability for reproducible, high efficiency separations. The Gemini family contains a variety of useful akyl and phenyl phases bonded to fully porous organo-silica particles.

 

Reversed Phase

Gemini C18 Phase

Gemini C18 HPLC phase offers unique reversed phase selectivity, high structural integrity, and increased loadability which make it ideal for preparative and purification applications in pre-packed columns and bulk media.

Gemini C6-Phenyl Phase

Gemini C6-Phenyl HPLC phase has a phenyl group bound to the organo-silica surface using a 6-carbon chain for a low bleed aromatic selective phase. Gemini C6-Phenyl is well suited for LC/MS applications.

Gemini NX-C18 Phase

The most rugged and highly efficient Gemini C18 HPLC column phase for reversed phase. Gemini NX-C18 takes LC/MS separations to the next level and offers:

  • Control selectivity of ionizable compounds for optimized methods
  • Consistent performance in both volatile and non-volatile buffers
  • High and low pH methods

Gemini C8(3) Phase

Optimized Purification Media for Human Insulin and It's Analogues

    • Enhanced Robustness Against Caustic Regeneration Conditions
    • High Packing Efficiencies
    • Incredible Mechanical Strength

Typically insulin purification methodologies include vital steps for column efficiency tests, equilibration, loading, and multiple caustic washes. In particular, the high pH caustic washes are very important for the removal aggregate build up, however these wash steps typical diminish column lifetime quite substantially. With the improved chemical robustness and performance of Gemini C8(3) customers can now switch their focus to higher yields and purities and minimize operational down-time due to less frequent need to replace contaminated media.

QC Tested to ensure consistent selectivity for Insulin and Impurity

In conjunction with a media designed specifically for insulin purification, the Quality team at Phenomenex strives to ensure high reproducibility of Gemini 10µm C8(3) through numerous quality control steps throughout the manufacturing process, including a fit for purpose human insulin QC test. This elevated level of focus on quality ultimately results in a model product for large scale insulin purification.

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Quantitation Of Human Plasma And Breast Milk Thiamine Monophosphate (TMP) And Thiamine By Applying Impact™ Protein Precipitation Plate Technology With Gemini® 3?m NX-C18 Hplc Columns
pdf
FL52750321_W.indd
This datasheet provides guidelines on allowable adjustments to European Pharmacopoeia methods using various Phenomenex LC columns, including Gemini, Kinetex, Luna, and others.
pdf
Impact of pH on Improving the Purity and Yield for Preparative Separations Using Gemini®-NX LC Columns
Gemini-NX preparative columns. ... By neutralizing the charge on basic compounds under high pH mobile phase, resolution and retention are significantly improved. ... Baseline resolution can be mai...