Clarity™ LC BioSolutions
Each product in the Clarity BioSolutions portfolio has been designed to efficiently and effectively purify or characterize synthetic oligonucleotides used in biological research, therapeutic development and biochemical manufacturing.
- Easily separate N-1 failure sequences from target oligo with > 90% purities
- Trityl-off purification of DNA, RNA, Thioates, and modified/labeled oligonucleotides
- Preparative dimensions and particle sizes for loads > 5μmol
- Purify oligos up to 60 mer in length
- Excellent column for reversed phase HPLC quality control (QC) testing
LC-MS Analysis
Clarity Oligo-XT
- First choice for analytical to preparative scale chromatography
- pH stable 1-12
- 100% aqueous mobile phase stable
- Core-shell particle technology provides improved speed, resolution, and sensitivity
- Easily scale analytical LC-MS methods to preparative scale for isolation/purification
- 1.7µm particles offer increased performance over existing sub-2µm methods
Clarity Oligo-MS
- Select if alternative selectivity is needed for analytical scale chromatography
- pH stable from 1.5-8.5
- Core-shell particle technology provides improved speed, resolution, and sensitivity
- Easily transfer quantitative LC-MS methods to any system with 2.6µm particles
- 1.7µm particles offer increased performance over existing sub-2µm methods
Clarity Oligo-RP
- Select if alternative selectivity is needed for analytical to preparative scale chromatography
- pH stable from 1.0-12
- Silica-organic grafting to create composite particle for improved robustness
- Easily scale analytical LC-MS methods to preparative scale for isolation/purification