Biozen™ Biologics LC Columns
Explore Biozen LC Portfolio
With a new titanium BioTi™ biocompatible hardware to minimize priming, four particle platforms for optimal versatility and nine particle chemistries to maximize selectivity and sensitivity, Biozen UHPLC/HPLC columns are seamlessly designed to bring peace of mind to your analysis of biologics through:
- Charge Variant Analysis
- Aggregate Analysis
- Peptide Mapping
- Intact Mass Intact and Fragment Analysis
- Glycan Analysis
- Peptide Quantitation
- Drug Antibody Ratio (DAR)
- Oligonucleotide Characterization
Biocompatible Flow Path with BioTi™ Hardware
Keep your mind at ease knowing that we’ve minimized the need for priming with a new titanium infused biocompatible hardware and frit that doesn’t interfere with protein or peptide integrity!
4 Advanced Particle Platforms
All four of the Biozen particle platforms were individually designed and built by Phenomenex to take advantage of integral levels of performance, ruggedness, and reproducibility for protein characterization applications. Individually, each platform differs in the proprietary processing techniques used to control particle size and morphology.
- Pore Controlled Technology
- Monosized Polymeric Non-Porous
- Core-Shell Technology
- Thermally Modified Fully Porous
8 Particle Chemistries
- Biozen dSEC : 1.8 µm and 3 µm
- Biozen Intact XB-C8 : 3.6 µm
- Biozen WidePore C4 : 2.6 µm
- Biozen Glycan : 2.6 µm
- Biozen Oligo : 1.7 µm and 2.6 µm
- Biozen Peptide XB-C18 : 1.7 µm and 2.6 µm
- Biozen Peptide PS-C18 : 1.6 µm and 3 µm
- Biozen WCX : 6 µm
Inside Biozen BioTi Hardware
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UHPLC Pressure Rating More experimental design space
More experimental design space, with room to increase flow rates for increased throughput -
Better Controlled ID Versus PEEK Hardware
Improved column-to-column performance, providing more consistency and easier method validation -
Improved Recovery and Peak Shape
Better column-to-column consistency, ease of use, and troubleshooting -
Biocompatible Titanium Liner
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Biocompatible Titanium Frit
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Strong Stainless Steel Walls Help Prevent Movement Under Pressure
Inside Biozen Particle Platforms
Thermally Modified Fully Porous
Through a proprietary thermal processing series of steps, we eliminate micropores and further improve consistency, column efficiency, inertness, ruggedness, and reproducibility.
Core-Shell Technology
Using sol-gel processing techniques that incorporate nano structuring technology, a durable, homogeneous porous shell is grown on a solid silica core. This highly optimized process combined with industry leading column packing technology produces highly reproducible columns that generate extremely high efficiencies and sensitivity.
Monosized Polymeric Non-Porous
Meticulously controlled monosized particle technology secures incredible particle consistency that leads to improved and reliable efficiency. This innovative non-porous particle serves as the perfect backbone for complex ion-exchange chemistries.
Pore Controlled Technology
The Biozen dSEC columns are packed with low pore volume silica coupled with a proprietary hydrophilic diol-type bonded surface chemistry that prevents the silica surface from interacting with protein samples.