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Axon™ Digidata® 1550B Low-Noise Data Acquisition System plus HumSilencer

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High-resolution, low-noise digitizer with 50/60 Hz line-frequency noise elimination

Key Features of the Axon Digidata 1550B Digitizer

  • 50/60 hz noise cancellation

    HumSilencer is an advanced feature that learns, adapts, and eliminates local 50/60 Hz line-frequency noise patterns and associated high-frequency harmonics from incoming signal up to 20 V peak-to-peak.

  • Noise canceling

    HumSilencer is not a filter and has no effect on acquired signals. It causes no signal distortion such as frequency change, amplitude attenuation, phase shift, or DC voltage change.

  • Wide range of input signals

    Digidata 1550B digitizes a wide range of input signals from -10 to +10 V.

  • HumSilencer adaptation

    HumSilencer automatically recognizes changes in noise amplitudes and adapts by removing noise in less than one second.

  • Optimized for pCLAMP 11 Software

    The pCLAMP Software suite is the most widely-used patch-clamp electrophysiology data acquisition and analysis program for control and recording of voltage-clamp, current-clamp, and patch-clamp experiments.

  • Three configurations

    Three configurations are available: Digidata 1550B4 with four HumSilencer channels, Digidata 1550B1 with one HumSilencer channel, and Digidata 1550B0 without a HumSilencer channel.

Applications of Axon Digidata 1550B Low-Noise Data Acquisition System plus HumSilencer

  • Cellular Pathway Analysis
  • Digital Acquisition
  • Disease Research
  • Drug Discovery & Development
  • HumSilencer Technology

The digitizer that enables acquisition of patch-clamp data

The Axon Digidata® 1550B plus HumSilencer® is one of the most advanced analog-to-digital signal converters on the market, offering the innovative line synchronous noise-cancelling feature, HumSilencer. This advanced feature learns, adapts, and eliminates local 50/60 Hz line-frequency noise and high-frequency harmonics from incoming signals. The digitizer works with pCLAMPTM 11 Software for data acquisition and analysis. The software supports eight channels of analog acquisition and four acquisition modes.

Eliminate line-frequency noise

HumSilencer removes 50/60 hz line-frequency noise on up to four channels in parallel. The function is quickly enabled through a software checkbox.

Record high resolution traces

All eight analog input channels can be simultaneously digitized at an impressive sampling rate of 500 kHz per channel.

Digitize cellular network studies

With Digidata 1550B system, you can now record cellular networks without 50/60 Hz line-frequency noise in a single digitizer while saving money, time, and reducing hassle.

Specifications
Maximum input signal (total of noise + signal) ±10 V
Maximum noise amplitude 20 V, peak-to-peak (on a 0 V signal)
Noise cancellation Line-frequency (50 Hz / 60 Hz) and harmonics to 10 kHz
Cancellation response time < 1 second
Number of input channels 8 single-ended
Number of ADCs 8
Sampling rates 1 Hz - 500 kHz
Input range -10.000 V to +10.000 V
Input resistance >1 MΩ
Gain value 1
Number of channels 8
Number of DAC 8
Output range -10.000 V to +10.000 V
Output impedance < 0.5 Ω
Output short circuit to signal ground ±25 mA
Number of bits 8 (of 16) supported in software
Scope Dedicated trigger output
Output driver Advanced CMOS (AC) compatible
Output current ±4 mA source, cable
Type USB 2.0 braided
Length 3 meters
Input type TTL compatible
TAG Rising-edge sensitive
Resolution 16-bit
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Axon™ Patch-Clamp | Molecular Devices
The Axon Instruments portfolio offers a complete solution for patch-clamping experiments, including amplifiers, digitizers, software, and accessories. Their instruments are suitable for a wide range of experiments, from small single channel recordings to large macroscopic recordings. The addition of the Axon pCLAMP 11 Software Suite improves workflow, allowing for more efficient experiments and higher quality data.
pdf
Axon Digidata 1550B Plus HumSilencer | Molecular Devices
The Axon Digidata 1550B Low Noise Data Acquisition System is a next-generation digitizer from Molecular Devices. It offers high-resolution, low-noise signal digitization and has the added feature of single-click elimination of 50/60 Hz line-frequency noise up to four channels. It is designed for precision scientific applications, particularly in electrophysiology experiments. The built-in HumSilencer technology quickly learns and removes local line-frequency noise patterns from incoming signals.