ML-385(AB287109)
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MW 511.6 Da, Purity >=98%. A potent and selective Nrf2 inhibitor (Nrf2; IC50 = 1.9 μM). ML-385 blocks Nrf2 downstream target gene expression. ML-385 displays specificity and selectivity for NSCLC cells with KEAP1 mutation, which leads to gain of Nrf2 function.
| Shipped At Conditions | Blue Ice |
| Appropriate Long term Storage Conditions | Store at -20°C. |
| Clonality | - |
| Applications | - |
| Species Reactivity | - |
| Isotype | - |
| Conjugation | - |
| CAS Number | - |