HDM-201 (Siremadlin)(AB287060)
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MW 555.4 Da, Purity >=98%. Potent and highly specific MDM-2/p53 inhibitor. It binds to human MDM2 protein with a picomolar Ki value (0.21 nM). It activates p53 and induces robust p53-dependent cell cycle arrest and apoptosis in human p53 wild-type tumor cells.
| Shipped At Conditions | Blue Ice |
| Appropriate Long term Storage Conditions | Store at -20°C. |
| Clonality | - |
| Applications | - |
| Species Reactivity | - |
| Isotype | - |
| Conjugation | - |
| CAS Number | - |