CHIR-124(ab273615)

MW 419.9 Da, Purity >98%. Novel and potent Chk1 inhibitor (IC50 = 0.3 nM), 2,000-fold more potent than Chk2 (IC50 = 0.7 μM). Also, potently targets other kinases such as FLT3 (IC50 = 5.8 nM), PDGFR (IC50 = 6.6 nM), GSK-3 (IC50 = 23.3 nM) and Fyn (IC50 = 98.8 nM) .