KW2449(ab273596)
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MW 332.4 Da, Purity >98%. Multi targeted inhibitor of FLT3 ( with an IC50 of 6.6nM), abL, abL-T315I, and Aurora kinase. Tumor growth inhibition in FLT3-mutated xenograft model in vitro. Shows a potent and significant antitumor effect in a dose-dependent manner in MOLM-13 tumour xenograft model in vivo..
| Shipped At Conditions | Ambient - Can Ship with Ice |
| Appropriate Long term Storage Conditions | Store at -20°C. |
| CAS Number | 841258-76-2 |