TW-37(ab273490)

Name: TW-37(ab273490)
Brand: Abcam
SKU: ab273490-abcam
Price: 210 USD
Availability: OnlineOnly

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Tw 37 Ab273490 Chemical Structure Img39325

MW 573.7 Da, Purity >98%. Small-molecule inhibitor of BCL-2 (Ki = 0.29 Î¼M). Inhibits multiple BCL-2 family members including BCL-XL (Ki = 1.11 Î¼M) and MCL-1 (Ki = 0.26 Î¼M). Binds to the BCL-2 homology domain 3 (BH3) groove of BCL-2. Significant anti-proliferative and pro-apoptotic activity in lymphoma cells.