Ryuvidine(ab254235)
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MW 284.3 Da, Purity >98%. Inhibits (IC50 = 500 nM) KMT5A / SETD8 / Pr-SET7 and suppresses H4JK20 monomethylation in vitro. Weakly active against Cdk4 (IC50 = 6 μM). Induces S-phase accumulation in HEK-293 cells. Cytotoxic towards a number of human cancer cell lines. May induce the DNA damage response.
| Shipped At Conditions | Blue Ice |
| Appropriate Long term Storage Conditions | Store at -20°C. |
| CAS Number | 265312-55-8 |