SMIFH2 Formin FH2 Domain Inhibitor(ab218296)
$undefined
MW 377.2 Da, Purity >99%. Cell-permeable inhibitor of formin homology 2 (FH2) domains. Prevents formin-mediated actin nucleation (IC50 = ~15 μM) and processive barbed end elongation. Decreases the affinity of formin for the actin filament barbed end. Disrupts formin-dependent actin cytoskeletal structures in fission yeast and mammalian NIH 3T3 fibroblasts.
| Shipped At Conditions | Ambient - Can Ship with Ice |
| Appropriate Long term Storage Conditions | Store at +4°C. |
| CAS Number | 340316-62-3 |