Kifunensine, class I alpha-mannosidase inhibitor(ab215116)

MW 232.19 Da. Cell-permeable, potent, selective inhibitor of class I α-mannosidases. (IC50 = 20-50 nM for mung bean α-1,2-mannosidase I). Alkaloid originally isolated from the actinomycete Kitasatosporia kifunense. Used to suppress Endoplasmic Reticulum-Associated Degradation (ERAD) via the inhibition of endoplasmic reticulum-associated mannosidase activity.