CAY10574, Cdk9 kinase inhibitor(AB144423)
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MW 218.2 g/mol, Purity >95%. Potent, selective Cdk9 kinase inhibitor (IC50 = 350 nM). Moderate ATP-competitive Cdk2-cyclin E inhibitor (IC50 = 20 μM). Induces cell cycle arrest, decreasing S-phase. Shows antiproliferative effects (IC50 values are 33, 49, 64 and 62 μM for MCF7, HOS, G361, and K562 cells respectively).
| Shipped At Conditions | Ambient - Can Ship with Ice |
| Appropriate Long term Storage Conditions | Store at -20°C. |