SCD1 Inhibitor, SCD1(stearoyl-CoA desaturase 1) inhibitor(AB142089)

MW 387.9 Da, Purity >99%. Potent, selective SCD1 (stearoyl-CoA desaturase 1) inhibitor (IC50 = 4.5 nM). Inhibits the conversion of saturated, long-chain fatty acyl-CoAs to monounsaturated, long-chain fatty acyl-CoAs in vitro, when heptadecanoic acid and palmitic acid are used as the substrate (IC50 = 7.9 and 6.8 nM, respectively). Active in vivo. Orally bioavailable. Also available as a solid (ab142089).