Lipid Peroxidation (MDA) Assay Kit (Colorimetric/Fluorometric)(AB118970)

Lipid Peroxidation Assay performed on mouse sciatic nerve samples. Hichor M et al. used the TBARS assay / MDA assay ab118970 to study the role of LXRs in the regulation of oxidative stress in peripheral nerves.

They identified that in sciatic nerves in LXR knockout mice (LXRdKO), the MDA concentration was significantly increased, and that this was corrected by the treatment of mice with the anti-oxidant ROS scavenger N-acetylcysteine (NAC).

Image courtesy of Hichor et al. Sci Rep. 2018; 8: 2524. doi: 10.1038/s41598-018-20980-3. Reproduced under the Creative Commons license http://creativecommons.org/licenses/by/4.0/.

Lipid Peroxidation Assay performed on mouse sciatic nerve samples. Hichor M et al. used the TBARS assay / MDA assay ab118970 to study the role of LXRs in the regulation of oxidative stress in peripheral nerves.

They identified that in sciatic nerves in LXR knockout mice (LXRdKO), the MDA concentration was significantly increased, and that this was corrected by the treatment of mice with the anti-oxidant ROS scavenger N-acetylcysteine (NAC).

Image courtesy of Hichor et al. Sci Rep. 2018; 8: 2524. doi: 10.1038/s41598-018-20980-3. Reproduced under the Creative Commons license http://creativecommons.org/licenses/by/4.0/.

Measurement of MDA in human plasma (20 μl) and rat liver lysate (10 mg).

MDA assay standard curve.

Typical MDA standard calibration curve using colorimetric reading.

MDA assay standard curve.

Typical MDA standard calibration curve using fluorometric reading.