RNA Extraction Kits
RNA—whether derived from cells, blood or challenging formalin-fixed paraffin-embedded (FFPE) tissue samples—is particularly prone to degradation, posing a risk of losing valuable data, potential false positives and substantial financial resources invested in sequencing low-quality RNA.
Our reagent kits address this vulnerability by facilitating a gentle binding process to SPRI paramagnetic beads, ensuring the preservation of optimum RNA integrity during the extraction process. This capability safeguards against degradation-related pitfalls, promoting reliable results and preventing unnecessary expenses in the pursuit of high-quality RNA sequencing.
Tailored for diverse input sample types and collection devices, our viral RNA extraction kits—including RNAdvance Viral XP for higher throughput and RNAdvance Viral kit for challenging samples—provide versatile solutions. Enjoy the convenience of comprehensive support for reagents and automation methods from a single vendor while reliably extracting RNA from cells, eliminating the need for filtration or centrifugation.
With our SPRI paramagnetic bead-based chemistry, even the most challenging FFPE tissue samples can be processed for RNA extraction. Experience efficient RNA extraction from a wide range of tissues without the associated hazards of organic solvents.
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Features
Essential features of our RNA extraction kits
- The mRNA extraction kits are built on a proprietary SPRI paramagnetic bead-based technology, ensuring a reliable and efficient process for isolating RNA.
- The kits produce high-integrity intact RNA suitable for Next-Generation Sequencing (NGS) and various PCR-based applications, ensuring quality results in molecular biology research.
- Whether manual or automated, the kits offer flexibility in processing, accommodating different laboratory workflows for RNA extraction.
- Specifically designed for infectious disease and pathogen research, the kits generate high-integrity viral RNA with a demonstrated Limit of Detection (LoD) at 1 copy/μL for sensitive PCR-based applications.
- The viral RNA extraction process is automation-ready and easily adaptable to liquid handling platforms, providing efficiency and convenience in high-throughput settings.
- The kits consistently deliver a high yield of pure nucleic acids, ensuring reliable and reproducible results across diverse sample and tissue types.
- FormaPure XL RNA kits, backed by fragment analysis, demonstrate the isolation of RNA with the high integrity, even from decade-old tissue blocks.
- The RNA extraction process is scalable, allowing for adjustment based on throughput needs, making it suitable for both small- and large-scale applications.
- The kits showcase performance reliability with a variety of sample and tissue types, demonstrating their adaptability to different experimental requirements.
- The kits ensure a high recovery of total RNA from challenging tissue types—including soft, fibrous, and lipid-rich tissues—enhancing the versatility of the extraction process.
- Automation-friendly features make the RNA extraction process compatible with automated systems, streamlining workflows and increasing efficiency in the laboratory.
Applications
Applications of RNA Extraction and Isolation Kits
- RNA isolation kits are instrumental in studying gene expression patterns. By isolating high-quality RNA, these kits enable researchers to perform techniques like reverse transcription and quantitative PCR.
- mRNA extraction kits play a pivotal role in preparing samples for NGS, a powerful technique for comprehensive genomic analysis.
- In the field of infectious disease research, mRNA purification kits are utilized for isolating viral RNA from clinical samples. This is crucial for studying the genetic material of pathogens, enabling the detection, identification and characterization of viruses.
How do RNA extraction kits prevent RNA degradation?
The kits prevent RNA degradation by ensuring all regents have undetectable levels of RNAses. Therefore, preserving RNA integrity throughout extraction from different sample types.
What technology is used in your RNA extraction kits?
Our RNA extraction kits utilize proprietary SPRI paramagnetic bead-based technology for efficient and reliable RNA isolation, safeguarding RNA integrity.
What downstream applications are supported by RNA isolated with RNA extraction kits?
RNA isolated with the kits is suitable for a range of downstream applications, including NGS, various PCR-based applications, and gene expression analysis.
How long does the RNA extraction process take with the kits?
The RNA extraction process time can vary based on the specific kit and application, however, the efficiency of our kits ensure a streamlined and time-efficient process.
Do you offer RNA extraction kits with automation compatibility?
Yes, our RNA extraction kits are automation-friendly, providing compatibility with automated systems for streamlined workflows and increased efficiency in the laboratory.
What quality control measures are in place for the RNA extraction kits?
Our RNA extraction kits undergo rigorous quality control measures, ensuring consistent and reliable performance in terms of yield, purity and integrity of the extracted RNA.
Are your RNA extraction kits suitable for manual and automated processing?
Yes, our kits offer flexibility for both manual and automated processing, accommodating different laboratory workflows and ensuring convenience.
What types of samples can be processed using RNA isolation kits?
Our RNA isolation kits are tailored for various samples, including blood preserved in PAXgene tubes, Saliva or Swab Transport Media samples, and even challenging FFPE tissue samples.
How do reagent kits with SPRI paramagnetic beads ensure optimal RNA integrity?
Reagent kits with SPRI paramagnetic beads facilitate a gentle binding process, preserving optimal RNA integrity during extraction. This proprietary technology safeguards against degradation, ensuring consistent delivery of pure nucleic acids.