Revolutionize your analytical workflows with our advanced sample preparation clean-up solutions, meticulously designed to eliminate contaminants, enhancing chromatographic performance and elevating sample detection sensitivity. Our innovative approach not only ensures the purity of your samples but also empowers you to boost analyte concentrations under specific conditions, providing unparalleled precision in your analyses. Trust in our cutting-edge sample preparation technology to elevate the quality, cleanliness of samples and reliability of your results, setting a new standard in analytical excellence.

Overview

In various industries such as pharmaceuticals, clinical analysis, toxicology, environmental testing, agriculture, and food and beverage, samples often exhibit non-homogeneity, particulates, and challenging levels of interfering compounds attributed to the diverse matrices like aqueous solutions, urine, soil, plasma, or blood. Our cutting-edge sample preparation clean-up solutions addresses these challenges by efficiently removing contaminants, optimizing chromatographic performance, and enhancing sample detection prior to chromatography separations.

Leveraging techniques such as solid phase extraction (SPE), solid liquid extraction (SLE), protein precipitation, immunocapture, filtration and more, along with our controlled manufacturing process, our products are consistent lot-to-lot and we provide high accuracy when using in the laboratory.

Carefully managing factors such as solvent composition, flow rate, and column size ensures a seamless process from the top of the column down to the bottom, preventing issues such as air bubbles, extraction errors, and optimizing the efficiency of the chromatographic separation.

Our syringe chromatography filters are crafted for swift and effective filtration of virtually any solution before analysis, emphasizing superior flows rates and optimized pore sizes for diverse samples. Experience the benefits of our syringe filters, which offer superior filtration, extended column lifespan, reduced system downtime, minimal protein absorption, and overall high-quality filtration performance.

For even further ease of use for filtration, our filter vials are all-in-one products (vial, cap, syringe, and membrane filter) for quick and easy particulate-free sample, ready for use in LC, GC, or other analytical techniques.

We also carry a wide range of sample prep cartridges/tubes and high-throughput 96-well plates that provide high recoveries and clean extracts.

Features

Essential methods for Chromatography Sample Preparation

• Solid phase extraction (SPE): Our SPE products excels in the clean-up and concentration of target analytes from diverse sample matrices such as blood, urine, plasma, food, and environmental samples. This technique ensures precision and reliable extractions, offering a crucial step in sample preparation.
• Protein precipitation (PPT): Designed for efficiency, our PPT method rapidly removes proteins from plasma samples, streamlining the process and enhancing the purity of analytes for subsequent analysis, in a few easy steps. This is one the most useful techniques for samples with matrices such as whole blood, serum or plasma.
• Phospholipid removal (PLR): Tailored for biological samples, our PLR technique swiftly eliminates proteins and phospholipids, addressing common challenges in sample matrices and improving the overall quality of analyses.
• Filtration: Employing advanced filtration, our method removes particulates from various samples, safeguarding the integrity of your analytical system and ensuring accurate results.
• QuEChERS: The acronym stands for Quick, Easy, Cheap, Effective, Rugged, and Safe, reflecting our commitment to providing a comprehensive solution for multi-residue analysis in food and environmental samples. This method offers a quick and cost-effective approach in a kit format for both EN and AOAC methods without compromising efficiency and ruggedness.
• Supported/Solid liquid extraction (SLE): Utilizing high-efficiency solid support to mimic liquid-liquid extractions, our SLE method ensures optimal extraction of analytes, offering a robust and reliable sample preparation technique.
• β-glucuronidase removal: With in-well hydrolysis capabilities, our method enables the rapid removal of the enzyme, β-Glucuronidase, from urine samples, ensuring accurate analysis and efficient sample preparation prior to drug analysis.
• Magnetic beads: Leveraging magnetic beads using immunocapture techniques, our method facilitates effective protein and peptide isolation, providing a versatile and powerful tool for researchers and analysts working with complex biological samples.

Applications

Applications for Chromatography Sample Preparation

• Ideal for environmental samples like water, wastewater, soil, and sludge, our disposable syringe filters meet the demanding requirements of environmental analysis in a simple method.
• In drug discovery and DMPK work, our syringe filters, protein preciptation, SPE, or other clean up methods provide efficient filtration for complex samples like serum, urine, and otherbiological fluids.
• Crucial for removing particulate matter before injecting clinical samples, our filters with higher flow rates and throughputs reduce downtime in the fast-paced toxicology environment.
• Our sample preparation method is tailored for the efficient extraction of Per- and Polyfluoroalkyl Substances (PFAS) from complex environmental matrices. By employing advanced SPE techniques, we ensure the removal of contaminants, providing researchers and environmental analysts with purified samples for accurate PFAS analysis and contributing to the assessment of environmental contamination.
• In the realm of cannabis testing, our sample preparation method plays a pivotal role in extracting cannabinoids, or other target analytes, and removing dirty matrices, such as the flower, oil, or other substances. This ensures accurate potency determination, compliance with regulatory standards, and the production of reliable data for both recreational and medicinal cannabis products.
• When it comes to vitamin testing in complex food matrices, we offer a variety of sample preparation techniques. By efficiently isolating and concentrating vitamins, we enable precise analysis, ensuring that food manufacturers and researchers obtain accurate information on the nutritional content of diverse food samples, contributing to quality control and labeling compliance.
• More complex sample preparation such as SPE or SLE are versatile and well-suited for a range of environmental testing applications. Whether analyzing soil, water, or air samples, our technique ensures the effective extraction of target analytes while minimizing interference from complex matrices. This is crucial for environmental monitoring and compliance assessment across diverse industries.
• Addressing the complexities of diverse food matrices, our sample preparation method excels in multi-residue analysis. It provides a reliable and efficient means to extract and purify analytes, ensuring the safety and compliance of food products by detecting contaminants such as pesticides and herbicides. Our filters are routinely used for accurate testing of pesticides, herbicides, fungicides, flavors, and fragrances, especially in samples with high particulate or fibrous matter.

FAQs