ImageXpress® Micro Confocal High-Content Imaging System

The ImageXpress® Micro Confocal system is a high-content solution that can switch between widefield and confocal imaging of fixed and live cells. It can capture high quality images of whole organisms, thick tissues, 2D and 3D models, and cellular or intracellular events. The spinning disk confocal and sCMOS camera enable imaging of fast and rare events like cardiac cell beating and stem cell differentiation. WithMetaXpress software and flexible options like water immersion objectives to choose from, the system enables many confocal imaging applications from 3D assay development to screening.

• Acquire higher quality images

Capture excellent contrast, high resolution images with our proprietary AgileOptix™ spinning disk confocal technology, wide field of view, and bright light source.

• Customize image acquisition and analysis

Take ultimate control over acquisition and analysis parameters, which enables many applications from 3D structure analysis to target imaging of specific objects within an organism or cell population. Run more applications with standard options like water immersion objectives, environmental control, or any of our high-performance customizations.

• Analyze more data in less time

MetaXpress® PowerCore™ software accelerates analysis speed in a high-throughput environment. The software distributes image processing jobs to a multi-CPU environment.

• Wide dynamic range

Quantify low and high-intensity signals in a single image with >3 log dynamic range intensity detection.

• Exclusive AgileOptix spinning disk confocal

The technology provides increased sensitivity with specially designed optics, high-powered, solid-state light engines, and an sCMOS sensor. Swappable disc geometries provide flexibility between speed and resolution.

• Wide field of view

A wide field of view enables whole-well confocal imaging and eliminates missed targets.

• Optional on-board robotic fluidics

For assays that involve compound addition, well washing, and media exchange, optional onboard robotic fluidics are available.

• Accurate 3D measurements

MetaXpress 3D analysis module is optimized for confocal imaging, enabling 3D measurements of volume and distance.

• Multiple imaging modes

The system offers phase contrast and brightfield label-free imaging, fluorescence, widefield, colorimetric, and confocal imaging, as well as, water immersion imaging as a standard option.

Our proprietary AgileOptix technology enables the ImageXpress Micro Confocal system to deliver the sensitivity and throughput needed for demanding applications. AgileOptix is the combination of a powerful solid-state, light engine, specially designed optics, a scientific CMOS sensor, and the ability to change disk geometries.

• Meet high throughput requirements with a scalable, streamlined workflow
• Adapt your analysis tools to tackle your toughest problems, including 3D analysis
• Schedule automatic data transfer between third-party hardware sources and secure database
• Set up hundreds of routinely used HCS assays using MetaXpress software modules

• 3D Cell Imaging and Analysis

• COVID-19 and Infectious Disease Research

• Cell Counting

• Cell Migration Assays

• Cells in Extracellular Matrices

• Disease Modeling

• Drug Discovery & Development

• Live cell imaging

• Neurite Outgrowth / Neurite Tracing

• Oncology - Cancer Research

• Organ-on-a-Chip

• Spheroids

• Stem Cell Research

• Toxicology