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BioPhase™ 8800 system

The BioPhase 8800 capillary electrophoresis system is a multi-capillary instrument designed for efficiency and ease-of-use operation for the analysis of purity and heterogeneity of biotherapeutics and the characterization of protein, peptides, nucleic acids and other molecular species.

Multiply your results. Multiply your success. Accelerate the development of your biotherapeutics.

Innovated from the ground up, the SCIEX BioPhase 8800 helps biopharmaceutical labs take charge of their development pipelines.

 

Scientists can now assess molecular liabilities more quickly, allowing rapid developability assessment to streamline the selection of candidates to be progressed into an effective therapy.

 

Run more samples, and more molecules, on a single system through not one, but eight capillaries in parallel.

Existing approaches to detect and characterize changes during the development of monoclonal antibodies (mAbs), next-generation therapeutics, and gene therapies are challenged to deliver the detailed information you need, in the time you need it.

 

 

The BioPhase 8800 system facilitates the parallel processing of eight samples simultaneously, while retaining the capability to deliver sensitive CE-SDS, RNA, cIEF and glycan characterization analysis enabling uncompromised accuracy for large sample sets and faster time to answers.

 

Expand

Take on multiple molecules, and multiple applications in less time - all on a single platform.

 

 

Accelerate

Shorten the time to market with high-throughput, 8 capillary analytics.

 

 

Simplify

With user-friendly software and pre-packaged

 

Explore the BioPhase 8800 system.

Delivering consistent, comparable and compliant data at scale across the biologic development continuum, the SCIEX BioPhase 8800 provides high-throughput, high-sensitivity analysis for bioprocessing, analytical development, and QA/QC, all in one system.

 
 

Take charge of your development timelines.

 

  • Adapt to your ever-changing drug pipeline

         Easily handle new and more complex molecules and their new analytical challenges.

 

  • Reduce method development time

        8 channels combined with validated kits and simplified software shorten the time from start up to answer.

 

  • Sensitive impurity quantification you can trust

        With high-sensitivity UV and Laser Induced Fluorescence detectors the BioPhase 8800 generates results you can trust.

 

Confident answers at warp speed.

Increase speed to market by making confident decisions quickly based on sensitive, high-resolution data that you’ve come to trust from SCIEX. This speed of analysis helps retain sample integrity between the first sample and the last – delivering consistent, accurate characterization and quantification for large samples sets, FAST.

Fast glycan

The BioPhase 8800 system provides parallel processing of eight glycan samples simultaneously, enabling high throughput glycan analysis workflows. With the Fast Glycan Labeling and Analysis kit, data collection in less than one minute per sample with highly robust and exceptional performance shortens development time while providing reliable CQA analysis.

 

CE-SDS

 

The BioPhase 8800 system provides automated, quantitative and repeatable capillary electrophoresis sodium dodecyl sulfate (CE-SDS) separations, delivering high-resolution purity analysis to help you keep pace with workloads while also minimizing sample prep and processing time.

 

 

 

cIEF

 

The BioPhase 8800 system delivers rapid and reproducible charge heterogeneity analysis via multi-capillary isoelectric focusing. Parallel processing of 8 samples simultaneously allows for significant improvements in method development and optimization time.

 

 

RNA

 

The BioPhase 8800 system allows for seamless method transferability and multi-capillary throughput for a multitude of RNA species. The RNA 9000 Purity & Integrity kit with the BioPhase 8800 system combines high-throughput screening with ultra-high resolution analysis of RNA products.

 

 

Streamline your workflow

Validated assay kits simplify operation and minimize user error in core industry applications including CE SDS Protein Analysis, cIEF, Fast Glycan and RNA 9000 kits.

 

Factory-built, multi-capillary, temperature-controlled cartridges help to ensure maximum data reproducibility.

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Genome Integrity Analysis Of Adeno-Associated Viruses
Introduction ... In a world where drug development pipelines are growing exponentially, analytical scientists are looking for faster and innovative ways to remove bottlenecks without compromising t...
pdf
High-Resolution Characterization Of Both sgRNA And Cas9 mRNA In A Single Analysis ForCRISPR/Cas9 Applications
RNA vaccine and CRISPR (clustered regularly interspaced short palindromic repeats) reagents manufacturers are often challenged to accurately characterize and quantify differently sized RNA molecule...
pdf
Fast Glycan Labeling And Analysis Kit For The BioPhase 8800 System
This document is provided to customers who have purchased SCIEX equipment to use in the operation of such SCIEX equipment. ... This document is copyright protected and any reproduction of this docu...
pdf
mRNA-LNP Nucleic Acid Assessment From Distinct Formulations By Multi-Capillary Gel Electrophoresis
Analysis of mRNA-LNP nucleic acid
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CE-SDS Protein Analysis Kit - For the BioPhase 8800 System
This document is provided to customers who have purchased SCIEX equipment to use in the operation of such SCIEX equipment. ... This document is copyright protected and any reproduction of this docu...
pdf
CapillaryIsoelectricFocusing(cIEF) Kit FortheBioPhase8800System
This document is provided to customers who have purchased SCIEX equipment to use in the operation of such SCIEX equipment. ... This document is copyright protected and any reproduction of this docu...