Our comprehensive collection of unconjugated antibodies and antibodies conjugated to unique labels offer flexibility for a variety of applications, including flow cytometry, immunohistochemistry (IHC), and a range of biochemical assays.
Unconjugated antibodies
Our unconjugated antibodies are offered in carrier-free formulations, carefully designed for efficient custom labeling and conjugation processes. These could be primary antibodies that bind directly to the target antigen or secondary antibodies that bind to the primary antibody but do not carry any label. Free from common additives such as bovine serum albumin (BSA), sodium azide, and glycerol, these antibodies eliminate components that can hinder conjugation efficiency. Carrier-free formats can be directly used in conjugation reactions without the hassle of buffer exchanges or concentration steps, helping reduce sample loss and improve experimental consistency.
Metal-conjugated antibodies
Our metal-conjugated antibodies are specifically engineered for high-precision applications, such as mass cytometry and multiplex imaging. Conjugated with stable metal isotopes, they enable detailed cell profiling and imaging with minimal spectral overlap, a critical advantage for analyzing complex samples. By delivering rich, high-dimensional datasets, these antibodies allow researchers to explore cellular behaviors, immune responses, and tumor microenvironment heterogeneity with enhanced clarity and confidence.
Oligonucleotide-conjugated antibodies
Designed for specialized molecular techniques, our oligonucleotide-conjugated antibodies serve essential roles in methods such as proximity ligation assays (PLA) and DNA-based barcoding systems. Through the integration of precise oligonucleotide sequences, these antibodies facilitate sensitive detection of protein-protein interactions and support high-throughput screening approaches. Their high specificity and sensitivity make them ideal tools for advanced applications in molecular biology, genomics, and proteomics research.
Other innovative labels
Beyond traditional formats, we offer antibodies conjugated to a variety of innovative labels, including nanoparticles and enzymes. Nanoparticle-conjugated antibodies expand the possibilities for imaging and biosensing technologies, providing unique signal enhancement and visualization capabilities. Enzyme-conjugated antibodies, on the other hand, enable robust signal amplification in biochemical assays, improving detection thresholds and assay performance.
Features
- Carrier-free formats: Our unconjugated immunoglobulins are offered in carrier-free formulations, free from additives like BSA, sodium azide, and glycerol. This purity ensures superior efficiency in labeling and conjugation processes without the need for additional purification steps.
- High sensitivity and specificity: Each antibody is developed to provide highly sensitive detection and outstanding specificity for target molecules. This design helps obtain reliable and accurate experimental outcomes across various assays.
- Versatile applications: Our antibodies are compatible with a broad range of research techniques. Their flexibility makes them suitable for both basic research and complex experimental studies.
- User-friendly protocols: We provide clear and easy-to-follow protocols that simplify the workflow for users at all technical levels. These streamlined procedures help save time and minimize experimental errors.
- Validated reagents: All our antibodies and reagents undergo rigorous validation.
- Automation-ready: Many of our antibody products are fully compatible with automated systems, enabling seamless integration into high-throughput workflows. This compatibility boosts efficiency and supports large-scale experimental operations.
Applications
- Flow cytometry: Metal-conjugated antibodies are ideal for achieving precise cell analysis and sorting, offering the advantage of minimal spectral overlap during flow cytometry experiments.
- Immunohistochemistry (IHC): Unconjugated and carrier-free antibodies provide dependable and high-quality staining results for tissue samples in immunohistochemistry applications.
- Mass cytometry: Researchers can utilize metal-conjugated immunoglobulins to perform high-dimensional data analysis and multiplex imaging, enhancing the depth and resolution of mass cytometry studies.
- PLA: Oligonucleotide-conjugated antibodies are used to detect protein-protein interactions with high sensitivity in PLA workflows.
- Biochemical assays: Enzyme-conjugated antibodies can be employed to significantly amplify signals in a wide range of biochemical assays, improving detection sensitivity.
- Imaging and biosensing: Nanoparticle-conjugated antibodies are applied in advanced imaging and biosensing technologies, offering unique advantages for sensitive detection and visualization.
- Multiplex IHC: Carrier-free antibodies are ideal for multiplex IHC, making it easier for researchers to perform high-dimensional tissue analysis and uncover the complexities of cellular environments.
What are carrier-free antibodies?
Carrier-free antibodies are made without the need for additives like BSA, sodium azide, or glycerol. By excluding these substances, they are better suited for direct labeling and conjugation, making them a great choice for researchers who need reliable, high-quality results in their experiments without worrying about interference from these additives.
Why use metal-conjugated antibodies?
Metal-conjugated antibodies are perfect for advanced techniques like mass cytometry and multiplex imaging. They help researchers gather detailed, high-dimensional data while minimizing the issue of spectral overlap, making it easier to analyze complex biological samples with greater precision.
What are oligonucleotide-conjugated antibodies used for?
Oligonucleotide-conjugated antibodies are commonly used in techniques such as proximity ligation assays (PLA) and DNA-based barcoding. These advanced methods allow researchers to detect protein-protein interactions with exceptional sensitivity, enabling deeper insights into cellular processes and molecular relationships.
What are the advantages of nanoparticle-conjugated antibodies?
Nanoparticle-conjugated antibodies offer unique detection capabilities for enhanced imaging and biosensing. Their properties improve sensitivity and enable novel analytical applications.
How do enzyme-conjugated antibodies work?
Enzyme-conjugated antibodies are designed to boost the signal in biochemical assays. They work by attaching to specific target molecules, and when activated, the enzyme produces a detectable signal that is much stronger than the original signal. This amplification helps researchers detect even small amounts of the target with high sensitivity and precision, making the detection process both more accurate and reliable.